Sökning: "progressive renal damage"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden progressive renal damage.

  1. 1. 99mTc-DMSA renal scintigraphy in the diagnosis and follow-up of acute pyelonephritis in children

    Författare :Lena Wallin; Lund Klinisk fysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomography; radiology; Clinical physics; progressive renal damage; kidney length; kidney radioactive uptake; pyelonephritis; DMSA-scintigraphy; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : The aim of the present thesis was to define and evaluate a strategy for identification of children who are at risk of developing progressive renal lesions after acute pyelonephritis. Tc-DMSA renal scintigraphy is widely accepted as the most sensitive method for detecting parenchymal lesions and diagnosing acute pyelonephritis. LÄS MER

  3. 2. Aspects of Regulation of GFR and Tubular Function in the Diabetic Kidney : Roles of Adenosine, Nitric Oxide and Oxidative Stress

    Författare :Patrik Persson; Fredrik Palm; Peter Hansell; Bengt Rippe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; diabetic nephropathy; glomerular filtration rate; renal blood flow; insulin; renal hemodynamics; micropuncture; oxygen; NADPH-oxidase; apocynin; streptozotocin; l-arginine; CGS21680; rats; mice; Physiology; Fysiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Diabetic nephropathy is the main cause for initiation of renal replacement therapy and early symptoms in patients include increased glomerular filtration rate (GFR), decreased oxygen tension and albuminuria, followed by a progressive decline in GFR and loss of kidney function. Experimental models of diabetes display increased GFR, decreased tissue oxygenation and nitric oxide bioavailability. LÄS MER

  4. 3. Role of new podocyte-associated proteins in the renal ultrafiltration barrier

    Författare :Angelina Schwarz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) is a major health problem and an economical burden affecting people worldwide. The main causes of CKD are diabetes and hypertension and patient numbers keep increasing. LÄS MER

  5. 4. Glomerular expression profiling and novel proteins in normal mouse kidney and adriamycin-induced nephrosis

    Författare :Masatoshi Nukui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kidney glomeruli function as high-capacity molecular sieves through which plasma is filtered into the Bowman s space as primary urine. The glomerular filtration barrier is composed of glomerular endothelial cells, the glomerulus basement membrane and the podocyte cell layer. LÄS MER

  7. 5. Nephroprotective effect of the cardiotonic steroid ouabain

    Författare :Ievgeniia Burlaka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA. LÄS MER