Sökning: "Yang Yang"

Visar resultat 16 - 20 av 326 avhandlingar innehållade orden Yang Yang.

  1. 16. Strategies to overcome drug resistance in FLT3+ AML

    Författare :Jingmei Yang; Ran Friedman; Merja Heinäniemi; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Biochemistry;

    Sammanfattning : Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor survivalrate and limited therapeutic options. Targeted treatment of other types ofcancer, for instance chronic myeloid leukemia (CML) and breast cancer, has seensignificant progress. LÄS MER

  3. 17. Regulation of artemisinin biosynthesis in Artemisia annua L

    Författare :Ke Yang; Peter E. Brodelius; Åke Strid; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; regulation of artemisinin biosynthesis; Artemisia annua transcription factors; AaMYB1; wounding treatment; promoter cloning; GC-MS; qPCR; Biokemi; Biochemistry; Mikrobiologi; Microbiology;

    Sammanfattning : Artemisinin and its derivatives are the most powerful medicines against malaria. However,the low annual yield of artemisinin from industry restricts the usage of this effective drug inendemic areas such as Africa. Nowadays the artemisinin industry mainly depends onextractions from Artemisia annua L. LÄS MER

  4. 18. Novel cycles using carbon dioxide as working fluid : new ways to utilize energy from low-grade heat sources

    Författare :Yang Chen; Per Gunnar Lundqvist; Mats Westermark; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Thermal energy engineering; Termisk energiteknik;

    Sammanfattning : This licentiate thesis proposes and analyzes three carbon dioxide novel cycles, namely: the carbon dioxide transcritical power cycle, the carbon dioxide Brayton cycle and the carbon dioxide cooling and power combined cycle. Due to the different characteristics of each cycle, the three cycles are suitable for different applications. LÄS MER

  5. 19. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

    Författare :Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER

  7. 20. Alzheimer disease : subcellular Aβ mechanisms and treatment strategies

    Författare :Yang Gao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The amyloid β-peptide (Aβ) is the key molecule in the pathogenesis of Alzheimer disease (AD), but the mechanisms of its toxicity are still largely unknown. This thesis includes studies aimed at studying Aβ induced mechanisms in neurons at the subcellular level and explore effective AD treatment strategies. LÄS MER