Sökning: "Ran Friedman"

Hittade 2 avhandlingar innehållade orden Ran Friedman.

1. 1. Modelling the evolution of treatment-induced resistance in Ph+ leukaemias

   Författare :Jonathan Lindström; Ran Friedman; Arne Traulsen; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic myeloid leukaemia; Stochastic modelling; Tyrosine kinase inhibitor; Drug resistance; Clonal evolution; Biomedical Sciences; Biomedicinsk vetenskap; Medicinsk kemi; Medical Chemistry;

   Sammanfattning : Targeted therapies are a mainstay of modern cancer treatments. Rather than harming rapidly dividing cells in general, targeted therapies work by directly interfering with oncogenic molecular pathways present in a tumour. Consequently, a targeted therapy typically has less severe side effects. LÄS MER

3. 2. Strategies to overcome drug resistance in FLT3+ AML

   Författare :Jingmei Yang; Ran Friedman; Merja Heinäniemi; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Biochemistry;

   Sammanfattning : Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor survivalrate and limited therapeutic options. Targeted treatment of other types ofcancer, for instance chronic myeloid leukemia (CML) and breast cancer, has seensignificant progress. LÄS MER