Sökning: "promoter cloning"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden promoter cloning.

1. 1. Regulation of artemisinin biosynthesis in Artemisia annua L

   Författare :Ke Yang; Peter E. Brodelius; Åke Strid; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; regulation of artemisinin biosynthesis; Artemisia annua transcription factors; AaMYB1; wounding treatment; promoter cloning; GC-MS; qPCR; Biokemi; Biochemistry; Mikrobiologi; Microbiology;

   Sammanfattning : Artemisinin and its derivatives are the most powerful medicines against malaria. However,the low annual yield of artemisinin from industry restricts the usage of this effective drug inendemic areas such as Africa. Nowadays the artemisinin industry mainly depends onextractions from Artemisia annua L. LÄS MER

3. 2. Positional cloning of polymorphic loci that control autoreactive T cells

   Författare :Mike Aoun; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Autoimmune diseases are expensive diseases, both financially and socially, because they are in most cases life long and require a long-lasting treatment. They can also be life threatening, as they are among top 10 causes of death in women and therefore, they represent a serious clinical problem and require careful medical management. LÄS MER

4. 3. Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I

   Författare :Per J G Lindquist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Acyl-CoA thioesterase; acyl-CoA; peroxisome proliferator-activated receptor alpha; fatty acid metabolism;

   Sammanfattning : Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the type I family of acylCoA thioesterases. These enzymes hydrolyze acyl-CoAs to non-esterified fatty acids (NEFAs) and Coenzyme A (CoA-SH) and are strongly induced in rodent liver by a diverse group of compounds called peroxisome proliferators. LÄS MER

5. 4. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

   Författare :Per Antonson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

   Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER

7. 5. Nephrin-mutations in congenital nephrotic syndrome of the Finnish type and cell lineage specific gene regulation

   Författare :Olga Beltcheva; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Nephrin; NPHS 1; CNF; podocytes; promoter;

   Sammanfattning : Kidneys, the main excretory organs in vertebrates, play central role in removing water soluble metabolic waste products from the organism. Many acquired and inherited renal diseases in man lead to kidney dysfunction and nephrotic syndrome - life-threatening condition affecting increasing number of people in the modem society. LÄS MER