Sökning: "Vascular Endothelial Growth Factor"

Visar resultat 16 - 20 av 184 avhandlingar innehållade orden Vascular Endothelial Growth Factor.

1. 16. On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors

   Författare :Karin Aase; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been shown to play an important role in the development of both blood and lymphatic vessels. LÄS MER

3. 17. New Roles of Filamins in Cell Signaling, Transcription and Organ Development

   Författare :Xianghua Zhou; Göteborgs universitet; []
   Nyckelord :filamins; cell movement; hypoxia-inducible factor 1; proto-oncogene proteins c-met; mice; knockout; F-actin-binding proteins; integrins; GTB phosphohydrolases; genetic diseases; inborn; vascular endothelial cell growth factor A; Smad2 protein; hepatocyte growth factor; cartilage; osteogenesis; neovascularization; neoplasm metastasis;

   Sammanfattning : Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin networks and link them to cellular membranes. They integrate cell architectural and signaling functions and are essential for cell locomotion and development. LÄS MER

4. 18. Fibroblast Growth Factor Receptor-1 Function in Vasculo- and Angiogenesis

   Författare :Peetra Magnusson; Lena Claesson-Welsh; Anne Eichmann; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR-1; VEGFR-2; PDGFR-β; endothelial cells; embryonic stem cell; angiogenesis; hematopoiesis; Patologi; Pathology; Patologi;

   Sammanfattning : During development of the mammalian embryo, spatial and temporal expression of fibroblast growth factors (FGFs) and their cognate receptors are vital in the regulation of a number of patterning processes. Inappropriate or decreased expression leads to severe malformations and even embryonic death. LÄS MER

5. 19. Collagenous Colitis : A Study of Inflammatory Mediators and Growth Factors Based on Segmental Colorectal Perfusion and Immunohistochemistry

   Författare :Yesuf Ahmed Taha; Magnus Thörn; Yngve Raab; Lars Lööf; Mikael Lördal; Curt Tysk; Uppsala universitet; []
   Nyckelord :General; Collagenous; Collagenous colitis; inflammatory mediators; Steroid treatment; Eosinophil Cationic Protein; Basic Fibroblast Growth Factor bFGF ; Vascular Endothelial Growth Factor VEGF ; albumin; ALLMÄNT;

   Sammanfattning : Collagenous colitis (CC) is an inflammatory bowel disease of unknown etiology. It is characterized by watery diarrhoea without blood, normal endoscopic findings but microscopically colonic mucosal inflammation and increased thickness of the subepithelial collagen band, the latter being a pathognomonic sign. LÄS MER

7. 20. Search for Biomarkers in ALS and Parkinson's Disease : Positron Emission Tomography and Cerebrospinal Fluid Studies

   Författare :Anders Johansson; Håkan Askmark; Lennart Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyotrophic lateral sclerosis; ALS; Parkinson’s disease; cerebrospinal fluid; positron emission tomography; vascular endothelial growth factor; fibroblast growth factor 2; proteomics; Fourier transform ion cyclotron resonance mass spectrometry; deprenyl-D2; PIB; FDG; L-[β11C]-DOPA; Neurology; Neurologi; Neurology; neurologi;

   Sammanfattning : New biomarkers are needed to improve knowledge about pathophysiology, in order to provide earlier correct diagnosis and to follow disease progression of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The aim of this thesis was to find new biomarkers for these diseases. LÄS MER