Sökning: "VLDL"

Visar resultat 6 - 10 av 50 avhandlingar innehållade ordet VLDL.

  1. 6. GH, IGF-1 and insulin in the regulation of lipid and lipoprotein metabolism

    Författare :Fredrik Frick; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth-hormone; insulin-like growth factor-I; insulin; lipoprotein lipase; adipose tissue; muscle tissue; VLDL secretion;

    Sammanfattning : It is well known that growth hormone (GH) has profound effects on lipid and lipoprotein metabolism. Insulin-like growth factor-I (IGF-I) is believed to mediate some of the effects of GH via endocrine and paracrine mechanisms. Moreover, both GH and IGF-I are known to influence insulin secretion. LÄS MER

  3. 7. A compartmental model for kinetics of Apolipoprotein B-100 and Triglycerides in VLDL_1 and VLDL_2 in normolipidemic subjects

    Författare :Martin Adiels; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 8. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

    Författare :Björn Magnusson; Göteborgs universitet; []
    Nyckelord :ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

    Sammanfattning : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. LÄS MER

  5. 9. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

    Författare :Jeanna Perman; Göteborgs universitet; []
    Nyckelord :very low density lipoprotein receptor; lipid accumulation;

    Sammanfattning : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. LÄS MER

  7. 10. Regulation of plasminogen activator inhibitor-1 : role of triglyceride-rich lipoproteins, fatty acids and fibrate compounds

    Författare :Lennart Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :plasminogen activator inhibitor-1; coronary heart disease; endothelial cells; very low density lipoprotein VLDL ; 4G 5G polymorphism; VLDL response element; fibrate compounds; VLDL receptor; stroke;

    Sammanfattning : Impaired fibrinolytic function secondary to elevated plasma plasminogen activator inhibitor-1 (PAI-1) activity is associated with atherothrombotic disease, in particular coronary heart disease. Both environmental and genetic factors contribute to determine plasma PAI-1 levels and PAI-1 production in vivo. LÄS MER