Sökning: "foam cell"

Visar resultat 1 - 5 av 64 avhandlingar innehållade orden foam cell.

1. 1. Transcriptional and post-transcriptional regulation of vascular smooth muscle cell phenotype - Implications for vascular disease states

   Författare :Azra Alajbegovic; Molekylär kärlfysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Vascular smooth muscle cells VSMC ; cell phenotype; microRNA; Aneurysm; hypertension; Actin polymerization; GATA6; MRTFA; Vascular disease;

   Sammanfattning : As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. LÄS MER

3. 2. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

   Författare :Björn Magnusson; Göteborgs universitet; []
   Nyckelord :ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

   Sammanfattning : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. LÄS MER

4. 3. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?

   Författare :Linda Svensson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; diabetes CD14; CD36; CD64; fatty acid; flow cytometry; macrophage; monocyte; scavenger receptor;

   Sammanfattning : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. LÄS MER

5. 4. Micro-structural based acoustic modelling of anisotropic open cell materials

   Författare :Eva Lundberg; Huina Mao; Bradley Semeniuk; Peter Göransson; Mathieu Gaborit; Romain Rumpler; Peter Göransson; Elke Deckers; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; sound absorption; vehicle; anisotropic; foam; micro-structure; resource efficient; transfer matrix method; ljudabsorption; anisotrop; skum; mikrostruktur; TMM; fordon; resurseffektiv; Farkostteknik; Vehicle and Maritime Engineering;

   Sammanfattning : A method for the calculation of the acoustic performance of open-cell foammaterials is discussed. From a known micro-structural geometry and theconstituent material, the relevant acoustic properties are computed using apreviously published analytical method for the calculation of the dynamicdrag impedance and a previously published method for the calculation of theelastic moduli. LÄS MER

7. 5. Intracellular lipids and inflammatory activity in macrophage foam cells

   Författare :Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

   Sammanfattning : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. LÄS MER