Sökning: "lipid droplet"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden lipid droplet.

  1. 1. Cardiac lipid storage and metabolism following myocardial ischemia

    Författare :Christina Drevinge; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipid accumulation; Myocardial Ischemia; Lipid droplets; Perilipin2; Perilipin5;

    Sammanfattning : Myocardial ischemia is associated with cellular- and metabolic adjustments within the heart, including accumulation of lipids. Myocardial lipids are stored in cytosolic droplets, consisting of a core of neutral lipids surrounded by a complex surface containing proteins, such as perilipins. LÄS MER

  3. 2. Engineering Lipid Metabolism for Production of Oleochemicals in Saccharomyces cerevisiae

    Författare :Paulo Teixeira; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; oleochemicals; lipid homeostasis; Saccharomyces cerevisiae< i>; lipid metabolism;

    Sammanfattning : Oleochemicals are chemicals usually derived from plant oils or animal fat. Large use of plant oil derivatives as replacements for petroleum-derived chemicals brings sustainability issues from extensive cultivation of oil plants in restricted regions. LÄS MER

  4. 3. The assembly of cytosolic lipid droplets and its effect on insulin sensitivity

    Författare :Pontus Boström; Göteborgs universitet; []
    Nyckelord :diabetes; lipid metabolism; insulin resistance; lipid droplets; ADFP; SNARE;

    Sammanfattning : Accumulation of neutral lipids, in particular triglycerides, in non-adipocytes is highly related to the development of insulin resistance and its consequences, type-2 diabetes and cardiovascular diseases. The accumulation of triglycerides occurs in so-called lipid droplets in the cytosol. LÄS MER

  5. 4. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation

    Författare :Björn Magnusson; Göteborgs universitet; []
    Nyckelord :ADP-ribosylation factor 1; very low density lipoprotein; lipid droplet; adipocyte differentiation-related protein; hypoxia; foam cell;

    Sammanfattning : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. LÄS MER

  7. 5. Intracellular lipids and inflammatory activity in macrophage foam cells

    Författare :Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

    Sammanfattning : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. LÄS MER