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Visar resultat 1 - 5 av 16 avhandlingar som matchar ovanstående sökkriterier.
1. Chromosomal β-lactamases in enterobacteria and in vivo evolution of β-lactam resistance
Sammanfattning : The ß-lactam antibiotics are the most important antibacterial agents in the treatment of infectious diseases. A severe problem in ß-lactam therapy is the emergence of ß-lactam resistant bacteria. Clinical ß-lactam resistance is most often due to the production of ß-lactamases. ß-lactamase genes reside either on plasmids or on the chromosome. LÄS MER
2. Modeling Neural Stem Cell and Glioma Biology
Sammanfattning : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. LÄS MER
3. Immunopathogenesis of relapsing fever borreliosis
Sammanfattning : Relapsing fever (RF) is caused by different species of Borrelia transmitted by soft ticks or by the human body louse. Illness is characterized by reappearing peaks of high concentrations of spirochetes in blood, concordant with fever peaks separated by asymptomatic periods. LÄS MER
4. Infection biology of Chlamydia pneumoniae
Sammanfattning : There are two main human pathogens in the family of Chlamydiaceae. Different serovars of Chlamydia trachomatis cause sexually-transmitted disease and eye infections whereas C. pneumoniae (TWAR) is a common cause of community-acquired respiratory infection. LÄS MER
5. Structure and Function of the Borrelia burgdorferi Porins, P13 and P66
Sammanfattning : Borrelia burgdorferi is an elongated and helically shaped bacterium that is the causal agent of the tick-borne illness Lyme disease. The disease manifests with initial flu-like symptoms and, in many cases, the appearance of a skin rash called erythema migrans at the site of the tick bite. LÄS MER