Sökning: "Structural Elucidation"

Visar resultat 6 - 10 av 57 avhandlingar innehållade orden Structural Elucidation.

1. 6. Structural and Interaction Studies of Bacterial Polysaccharides by NMR Spectroscopy

   Författare :Eva-Lisa Nordmark; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial polysaccharides; NMR; interaction studies; structural studies; Escherichia coli; Salmonella enteritidis; Streptococcus thermophilus; Propionibacterium freudenreichii; Pseudoalteromonas aliena; P22 TSP; Organic chemistry; Organisk kemi;

   Sammanfattning : An introduction to bacterial polysaccharides and the methods for structural determination are described in the first two parts of the thesis.In a structural elucidation of bacterial polysaccharides NMR experiments are important as is component analysis. A short description of immunochemical methods such as enzyme immunoassays is included. LÄS MER

3. 7. Deciphering Carbohydrate Structure : From NMR Chemical Shifts to Conformational Analysis

   Författare :Kevin M. Dorst; Göran Widmalm; Martina Delbianco; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR chemical shift prediction; Structural elucidation; Conformational studies; NMR spectroscopy; MD simulations; Organic Chemistry; organisk kemi;

   Sammanfattning : Carbohydrates are ubiquitous in nature and exhibit a multitude of roles. Besides nucleic and amino acids, they can be regarded as the third alphabet of life. They are used as energy source to fuel the cells, as structural building blocks and play a key role in cellular recognition processes. LÄS MER

4. 8. Secondary Metabolites from Mozambican Plants

   Författare :Julião Monjane; Centrum för analys och syntes; []
   Nyckelord :Secondary metabolites; Mozambique; Medicinal plants; Isolation; Structural elucidation; Antileishmanial activity;

   Sammanfattning : Products derived from different natural sources have been used for thousands of years by human beings for their everyday needs. Out of these natural sources, plants were the most affordable. Plant-derived products were used for shelter, food, and as medicines. LÄS MER

5. 9. Computer-Assisted Carbohydrate Structural Studies and Drug Discovery

   Författare :Magnus Lundborg; Göran Widmalm; Hans-Christian Siebert; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; molecular docking; molecular dynamics simulation; fragment-based virtual screening; NMR spectroscopy; computer-aided drug design; computer-aided structure elucidation; glycosyltransferases; Escherichia coli; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : Carbohydrates are abundant in nature and have functions ranging from energy storage to acting as structural components. Analysis of carbohydrate structures is important and can be used for, for instance, clinical diagnosis of diseases as well as in bacterial studies. The complexity of glycans makes it difficult to determine their structures. LÄS MER

7. 10. Structural elucidation of the O-antigen polysaccharides of five Escherichia coli strains

   Författare :Malin Linnerborg; Yuriy A. Knirel; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

   Sammanfattning : The cell walls of bacteria are composed to a large extent of different polysaccharides. In order to understand and thereby, be able to utilise the physical, biological and immunological properties of polysaccharides, it is important to determine their structures. LÄS MER