Sökning: "fragment-based virtual screening"
Hittade 2 avhandlingar innehållade orden fragment-based virtual screening.
1. Computer-Assisted Carbohydrate Structural Studies and Drug Discovery
Sammanfattning : Carbohydrates are abundant in nature and have functions ranging from energy storage to acting as structural components. Analysis of carbohydrate structures is important and can be used for, for instance, clinical diagnosis of diseases as well as in bacterial studies. The complexity of glycans makes it difficult to determine their structures. LÄS MER
2. Anti-Virulence Strategy Targeting Sortase A, A Structural Investigation of the Sortase A Enzyme, and the Identification, Synthesis, and Evaluation of Sortase A Inhibitors
Sammanfattning : The emergence of multi-resistant bacteria and their continuous spread is one of the greatest challenges when treating bacterial infections. Increased understanding of bacterial pathogenesis has revealed new strategies for treating bacteria-mediated diseases. LÄS MER