Sökning: "Hans-Christian Siebert"

Hittade 1 avhandling innehållade orden Hans-Christian Siebert.

1. 1. Computer-Assisted Carbohydrate Structural Studies and Drug Discovery

   Författare :Magnus Lundborg; Göran Widmalm; Hans-Christian Siebert; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; molecular docking; molecular dynamics simulation; fragment-based virtual screening; NMR spectroscopy; computer-aided drug design; computer-aided structure elucidation; glycosyltransferases; Escherichia coli; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : Carbohydrates are abundant in nature and have functions ranging from energy storage to acting as structural components. Analysis of carbohydrate structures is important and can be used for, for instance, clinical diagnosis of diseases as well as in bacterial studies. The complexity of glycans makes it difficult to determine their structures. LÄS MER