Sökning: "Rolf Larsson"

Visar resultat 31 - 35 av 54 avhandlingar innehållade orden Rolf Larsson.

  1. 31. Statistical Properties of Preliminary Test Estimators

    Författare :Nicklas Korsell; Rolf Larsson; Johan Lyhagen; Tore Schweder; Uppsala universitet; []
    Nyckelord :Statistics; Linear regression; Preliminary test; Model selection; Test for homoscedasticity; Variance components; Truncated estimators; Inertia of matrices; Statistik;

    Sammanfattning : This thesis investigates the statistical properties of preliminary test estimators of linear models with normally distributed errors. Specifically, we derive exact expressions for the mean, variance and quadratic risk (i.e. the Mean Square Error) of estimators whose form are determined by the outcome of a statistical test. LÄS MER

  3. 32. Characterization of Surfaces Designed for Biomedical Applications

    Författare :Emma Kristensen; Hans Siegbahn; Rolf Larsson; Sven Oscarsson; Uppsala universitet; []
    Nyckelord :Physics; heparin; photoelectron spectroscopy; phosphorylcholine; biomaterial; quartz crystal dissipation; Fysik; fysik; Physics;

    Sammanfattning : In order to develop blood biocompatible materials a heparin surface and a phosphorylcholine (PC) functionalized polymer surface were characterized using photoelectron spectroscopy (PES). The formation of the heparin surface was studied by quartz crystal microbalance with dissipation monitoring (QCM-D). LÄS MER

  4. 33. On Non Parametric Regression and Panel Unit Root Testing

    Författare :Xijia Liu; Rolf Larsson; Johan Lyhagen; Niklas Ahlgren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : In this thesis, two different issues in econometrics are studied, the estimation of regression coefficients and the non-stationartiy analysis in a panel setting.Regarding the first topic, we study a set of measure of location-based estimators (MLBEs) for the slope parameter in a linear regression model with a single stochastic regressor. LÄS MER

  5. 34. Pharmacology and resistance mechanisms of nucleoside analogues and topoisomerase II interactive agents : studies on human leukemia cells with a focus on cross-resistance

    Författare :Kourosh Lotfi; Rolf Larsson; Linköpings universitet; []
    Nyckelord :Nucleoside analogue; cross-resistance; multidrug resistance; deoxycytidine kinase; leukemia; anthracyclines; P-glycoprotein; MEDICINE; MEDICIN;

    Sammanfattning : The purpose of this thesis was to elucidate mechanisms of action and resistance of clinically relevant nucleoside analogues and topoisomerase interactive agents in human leukemia cell lines and leukernia cells isolated from peripheral blood of leukemia patients. Interactions and cross-resistance patterns of these different cytotoxic drug families were also studied since these drugs are usually administrated in combination in the clinic. LÄS MER

  7. 35. Cellular Pharmacology of the Novel Antitumoural Cyanoguanidine CHS 828

    Författare :Henrik Lövborg; Rolf Larsson; Peter Nygren; Klas Wiman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; CHS 828; Cyanoguanidines; Oncology; Pharmacology; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The antitumoural cyanoguanidine CHS 828 has shown promising activity in a number of preclinical and clinical studies. However, the mechanisms underlying the cell death induced by CHS 828 has not been clarified. This thesis describes in vitro studies of the cellular pharmacology of CHS 828. LÄS MER