Sökning: "Henrik Lövborg"

Hittade 2 avhandlingar innehållade orden Henrik Lövborg.

1. 1. Cellular Pharmacology of the Novel Antitumoural Cyanoguanidine CHS 828

   Författare :Henrik Lövborg; Rolf Larsson; Peter Nygren; Klas Wiman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; CHS 828; Cyanoguanidines; Oncology; Pharmacology; Farmakologi; Pharmacological research; Farmakologisk forskning;

   Sammanfattning : The antitumoural cyanoguanidine CHS 828 has shown promising activity in a number of preclinical and clinical studies. However, the mechanisms underlying the cell death induced by CHS 828 has not been clarified. This thesis describes in vitro studies of the cellular pharmacology of CHS 828. LÄS MER

3. 2. New Methods to Screen for Cancer Drugs and to Evaluate their Mechanism of Action

   Författare :Linda Rickardson; Rolf Larsson; Peter Nygren; Henrik Lövborg; Kjell Grankvist; Uppsala universitet; []
   Nyckelord :Pharmacology; Cancer drugs; Screening; Gene expression; Farmakologi;

   Sammanfattning : Cancer is a common disease and due to problems with resistance against cancer drugs and the limited benefit from chemotherapy in many diagnoses, there is a need to develop new cancer drugs. In this thesis new methods to screen for cancer drugs and to evaluate their mechanism of action are discussed. LÄS MER