Sökning: "Reactive oxygen species production"

Visar resultat 36 - 40 av 161 avhandlingar innehållade orden Reactive oxygen species production.

1. 36. The pathophysiology of respiratory chain dysfunction

   Författare :José Pablo Silva; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondrial disease; mitochondrial DNA mtDNA ; mitochondrial transcription factor A Tfam ; Cre-loxP; conditional knockout; reactive oxygen species ROS ; superoxide; uncoupling protein UCP ; mitochondrial bioenergeties; energy expenditure;

   Sammanfattning : Mutations of mitochondrial DNA cause a variety of clinical syndromes. It is unclear whether impaired oxidative phosphorylation on its own is the main cause of pathology or whether other factors such as secondary metabolic alterations, enhanced formation of reactive oxygen species (ROS) and induction of apoptosis also may contribute to the clinical phenotype. LÄS MER

3. 37. Characterisation of newt neural stem cells during development and regeneration

   Författare :Shahul Hameed Liyakath Ali; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The adult newt brain has a unique potential to regenerate neurons after injury. Ependymoglial cells that line the ventricular system of the newt brain are critical for neuronal regeneration, since they reenter the cell cycle upon injury and differentiate into neurons. Ependymoglial cells share key features with radial glial cells in mammals. LÄS MER

4. 38. The primed neutrophil : a friend or a foe in inflammation

   Författare :Per Follin; Staffan Ahlstedt; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Human neutrophils are the most abundant of the white blood cells in circulation and represent the first line of defense against invading microorganisms. With a membrane-bound enzyme system (the NADPH oxidase), these cells can generate reactive oxygen metabolites that serve efficiently in antimicrobial defense. LÄS MER

5. 39. Engineering the Secretory Pathway for Recombinant Protein Secretion in Saccharomyces cerevisiae

   Författare :Jichen Bao; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; endoplasmic reticulum; oxidative stress; GLO3; protein secretion; transcriptomics; drug screening; Saccharomyces cerevisiae; SEC16;

   Sammanfattning : In the past few decades there has been an increasing demand of biopharmaceutical proteins in the market. Several types of cell factories are applied to produce different pharmaceutical proteins. LÄS MER

7. 40. Photodynamic therapy in the head and neck

   Författare :Mathias von Beckerath; Claes Möller; Göran Laurell; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Photo Dynamic Therapy; Cancer; Skin; Larynx; 5-ALA; UVradiation; sarcoma; squamous cell carcinoma; porfimer sodium; temoporfin; voice; Kirurgi; Surgery;

   Sammanfattning : Photodynamic therapy, PDT, is a method to diagnose and treat cancer. In PDT a sensitizer is administered to the patient and this sensitizer is accumulated in tumors. If the sensitizer-containing tumor is subjected to a laser of a specific wavelength the tumor is fluorescing allowing diagnostics. LÄS MER