Sökning: "Protein Phosphatases"

Visar resultat 6 - 10 av 55 avhandlingar innehållade orden Protein Phosphatases.

1. 6. Regulation of leukocyte integrin adhesiveness

   Författare :Håkan Hedman; Erik Lundgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphocytes; Cell Adhesion; Integrins; LFA-1; VLA-4; ICAM-1; VCAM-1; Microvesicles; Protein Kinases; Protein Phosphatases;

   Sammanfattning : .... LÄS MER

3. 7. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases

   Författare :Camilla Persson; Arne Östman; Niels Peter Moller; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; protein tyrosine phosphatase; tyrosine kinase; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). LÄS MER

4. 8. Protein kinases and phosphatases in B-cell lymphoma

   Författare :Marie Fridberg; Tumörmikromiljö; []
   Nyckelord :HePTP; PTEN; PKC-beta 2; B-cell; lymphoma; kinases; ZAP70; phosphatase; SHP2;

   Sammanfattning : Around 2000 persons are diagnosed with lymphoma in Sweden each year. There are many subgroups described for this form of cancer and the great majority is derived from B-cells. The most common subgroup is Diffuse large B-cell lymphoma (DLBCL), a highly aggressive disease where only half of the patients are cured. LÄS MER

5. 9. Studies of nucleotide receptors-induced calcium response in glomerular mesangial cells and afferent arterioles

   Författare :Antonio M. Gutiérrez; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mesangial cells; nucleotide receptors; purinoceptors; desensitization; afferent arterioles; ATP; UTP; adenosine; protein phosphatases; calcium; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

   Sammanfattning : It is known that intracellular calcium concentration ([Ca2+]i) changes in rat glomerular mesangial cells (GMC) and rabbit afferent arterioles (AA) in response to extracellular nucleotides. We studied the nucleotide-induced calcium response in cultured GMC and AA. LÄS MER

7. 10. Protein tyrosine phosphatases : taking a 'redoxionist' look at PDGFR signaling

   Författare :Jeroen Frijhoff; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Protein Tyrosine Phosphatases (PTPs) are oxidized and inactivated by reactive oxygen species (ROS) upon stimulation of a wide range of cell surface receptors, including the platelet-derived growth factor (PDGF) receptor (PDGF R). Signaling via this receptor tyrosine kinase stimulates cell proliferation and migration, and it is associated with cancer and cardiovascular diseases. LÄS MER