Sökning: "nucleotide receptors"

Visar resultat 1 - 5 av 46 avhandlingar innehållade orden nucleotide receptors.

  1. 1. Studies of nucleotide receptors-induced calcium response in glomerular mesangial cells and afferent arterioles

    Författare :Antonio M. Gutiérrez; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mesangial cells; nucleotide receptors; purinoceptors; desensitization; afferent arterioles; ATP; UTP; adenosine; protein phosphatases; calcium; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : It is known that intracellular calcium concentration ([Ca2+]i) changes in rat glomerular mesangial cells (GMC) and rabbit afferent arterioles (AA) in response to extracellular nucleotides. We studied the nucleotide-induced calcium response in cultured GMC and AA. LÄS MER

  3. 2. Novel functions of cardiovascular P2 receptors

    Författare :Anna-Karin Wihlborg; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; mRNA; EDHF; UTP; UDP; ADP; ATP; P2 receptor; contraction; dilatation; endothelial cells; Heart; VSMC;

    Sammanfattning : The aim of the thesis was to examine the expression and function of the extracellular nucleotide P2 receptors in the cardiovascular system. In the cardiovascular system nucleotides are released during shear stress, hypoxia, ischemia, from endothelial cells, smooth muscle cells, aggregating platelets, inflammatory cells and erythrocytes. LÄS MER

  4. 3. Adrenergic receptors in brown adipose tissue

    Författare :Jan Svartengren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The purpose of this study was to identify adrenergic receptors and to investigate their regulation of physiological processes in brown adipose tissue.Isolated hamster brown fat cells and plasma membrane fractions contained a high number of α1- and β1-adrenergic receptors, as assessed by direct radioligand binding techniques using (3H)prazosin and (-)(3H)dihydroalprenolol, respectively. LÄS MER

  5. 4. Pattern-recognition receptors in airway inflammation

    Författare :Anna-Karin Ekman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. LÄS MER

  7. 5. Estrogen and liver X receptors in human disease

    Författare :Maria Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Estrogen Receptor; Liver X Receptor; polymorphism; Bulimia Nervosa; SNP; BMI; obesity; expression levels; T2D.;

    Sammanfattning : The nuclear hormone receptors (NRs) are a class of transcription factors that has attracted great interest due to their important roles in animal physiology and metabolism. Studies of knockout (KO) mouse models have indicated several pathophysiological conditions in which the NRs are involved. LÄS MER