Sökning: "PKC-beta 2"

Hittade 2 avhandlingar innehållade orden PKC-beta 2.

1. 1. Protein kinases and phosphatases in B-cell lymphoma

   Författare :Marie Fridberg; Tumörmikromiljö; []
   Nyckelord :HePTP; PTEN; PKC-beta 2; B-cell; lymphoma; kinases; ZAP70; phosphatase; SHP2;

   Sammanfattning : Around 2000 persons are diagnosed with lymphoma in Sweden each year. There are many subgroups described for this form of cancer and the great majority is derived from B-cells. The most common subgroup is Diffuse large B-cell lymphoma (DLBCL), a highly aggressive disease where only half of the patients are cured. LÄS MER

3. 2. Effect of hyperglycemia on glucose transport and intracellular signal transduction in skeletal muscle

   Författare :Yuichi Kawano; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :skeletal muscle; glucose transport; insulin signaling; hyperglycemia; PKC; Akt kinase; GotoKakizaki rat; phlorizin; muscle fiber type;

   Sammanfattning : Recent studies revealing the components of insulin signal transduction have raised the question of whether the defects in insulin signaling account for disturbed glucose metabolism in people with NIDDM. The major focus of this thesis is to elucidate the role of insulin signal transduction in the development of peripheral insulin resistance. LÄS MER