Sökning: "Arne Östman"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Arne Östman.

  1. 1. Platelet-derived growth factor: recombinant isoforms, structure/function relationships and design of a potential antagonist

    Författare :Arne Östman; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Human Epidermal Growth Factor Receptors and Biological Effects of HER-directed Molecules on Skin Epithelialization

    Författare :Sofi Forsberg; Ola Rollman; Arne Östman; Anders Vahlquist; Eva Hagforsen; Gunnar Kratz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatology and venerology; Dermatologi och venerologi;

    Sammanfattning : Human skin forms a biologically active barrier and maintains vital protective functions through continuous regeneration of cells within its outermost layer, the epidermis. In healthy skin, renewal of epithelial cells is a tightly regulated process in which the epidermal growth factor receptor (EGFR or HER1) and its various ligands are involved. LÄS MER

  4. 3. Myofibroblasts and the Vascular Endothelium : Impact of Fibrin Degradation Products and miRNA on Vascular Motility and Function

    Författare :Peder Fredlund Fuchs; Pär Gerwins; Johan Kreuger; Arne Östman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Angiogenesis; Vascular biology; Chemotaxis; Endothelial cell; Myofibroblast; Wound healing; miRNA; Heparan sulfate; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing vasculature and is important during development as well as wound healing and tissue remodeling. Angiogenesis also occurs during pathological conditions such as diabetic retinopathy and cancer. LÄS MER

  5. 4. Examining the prostate stroma and vasculature : importance and potential as targets for therapy

    Författare :Anna Johansson; Anders Bergh; Arne Östman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; castration therapy; vasculature; stroma; the angiopoietins; the PDGF-receptors; mast cells; Pathology; Patologi;

    Sammanfattning : Background. Recent studies in cancer research have focused on the reciprocal interaction between cancer cells and their microenvironment. Tumour growth is angiogenesis dependent and the rate of angiogenesis correlates with a poor prognosis in many different cancers. LÄS MER

  7. 5. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases

    Författare :Camilla Persson; Arne Östman; Niels Peter Moller; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; protein tyrosine phosphatase; tyrosine kinase; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). LÄS MER