Sökning: "Pfam"

Visar resultat 6 - 8 av 8 avhandlingar innehållade ordet Pfam.

  1. 6. Structured Learning for Structural Bioinformatics : Applications of Deep Learning to Protein Structure Prediction

    Författare :David Menéndez Hurtado; Arne Elofsson; Sergei Grudinin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Proteins are the basic molecular machines of the cell, performing a broad range of tasks, from structural support to catalysisof chemical reactions. Their function is determined by their 3D structure, which in turn is dictated by the order of their components, the amino acids. LÄS MER

  3. 7. On protein structure, function and modularity from an evolutionary perspective

    Författare :Robert Pilstål; Björn Wallner; Maria Sunnerhagen; Mauno Vihinen; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

    Sammanfattning : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. LÄS MER

  4. 8. Tools and annotations for variation

    Författare :Gerard C.P. Schaafsma; Proteinbioinformatik; []
    Nyckelord :Annotation; genetic variation; benchmarks; databases; disease groups; pathogenicity; proteins; representativeness; sensitivity; variant effect analysis;

    Sammanfattning : Since the finishing of the Human Genome Project, many next-generation (NGS) or high-throughput sequencing platforms have emerged. One of the applications of NGS technology, variant discovery, can serve as a basis for precision medicine. LÄS MER