Sökning: "PC12"

Visar resultat 11 - 15 av 46 avhandlingar innehållade ordet PC12.

  1. 11. Investigation on Pre- and Postsynaptic Ca2+ Signaling in Neuronal Model Systems

    Författare :Jelena Krjukova; Åkerman Karl; Kukkonen Jyrki; Rydqvist Bo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; calcium; neurotransmitter release; nicotine; depolarization; G-protein coupled receptor; muscarinic; phospholipase C; m-3M3FBS; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i elevations. LÄS MER

  3. 12. Analysis of phospholipids in cellular membranes with LC and imaging mass spectrometry

    Författare :Ingela Lanekoff; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; TOF-SIMS; Phospholipid; Cells; Anammox;

    Sammanfattning : Imaging mass spectrometry enables the creation of molecule specific images from the surface of a solid sample in vacuum. To solve the issue of bringing single cells into vacuum without altering their native distribution of molecules, a freeze fracture device that fits the time of flight secondary ion mass spectrometry (TOF-SIMS) IV instrument has been developed. LÄS MER

  4. 13. The Mechanisms of Exocytosis Studied in Cells and Models with Amperometry

    Författare :Lisa J. Mellander; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Exocytosis; Electrochemistry; Cells; Cell models; Phospholipids;

    Sammanfattning : Exocytosis is the universal basis for neuronal communication, allowing the controlled release of neurotransmitter molecules from the presynaptic cell. Exocytosis has been widely studied in many systems. However, the details of this vital process are not fully understood. LÄS MER

  5. 14. MIR, a novel ERM-like protein in the nervous system

    Författare :Per-Anders Olsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; MIR; ERM; band 4.1 superfamily; MRLC; NSAP; neurite outgrowth; nervous system; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Sammanfattning : Proteins of the band 4.1 superfamily are characterized by their sequence similarity to the ERM proteins ezrin, radixin and moesin, which are involved in cell motility, adhesion of cells, and signal transduction events. LÄS MER

  7. 15. Molecular mechanisms of metal toxicity in neuronal cells

    Författare :Annamaria Rossi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Modification of signal transduction by toxic agents can affect cell metabolism and physiological activity, impair cell capacity to adequately respond to hormones and growth stimuli and consequently compromise cell survival. This thesis describes studies on the interactions between toxic metals, at concentrations comparable to environmental exposure, and Ca2+ signalling in neuronal cells. LÄS MER