Sökning: "Nijmegen"

Visar resultat 6 - 10 av 12 avhandlingar innehållade ordet Nijmegen.

  1. 6. The Recontextualisation of Social Pedagogy. A study of three curricula in the Netherlands, Norway and Ireland

    Författare :Pelle Hallstedt; Mats Högström; Utbildningsvetenskap; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Pedagogy and didactics; Sociologi; Sociology; welfare state; social pedagogy; recontextualisation; pedagogic discourse; higher education; ethnography; discourse analysis; classification and framing; Basil Bernstein; curriculum; Pedagogik; didaktik; Special didactics; Specialdidaktik; Basil Bernstein;

    Sammanfattning : The purpose of this thesis is to describe, analyse, and compare the recontextualisation of social pedagogy in three different curricula; in Nijmegen (NL), Lillehammer (N), and Sligo (IRL). The curricula represent different academic orientations and are located in different social-political contexts. LÄS MER

  3. 7. Functional analysis of ATM with relevance for primary immunodeficiency and tumor formation

    Författare :Aleksi Lähdesmäki; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by cerebellar degeneration with ataxia, ocular and cutaneous telangiectasias, radiosensitivity, chromosomal instability, immunodeficiency, and cancer predisposition in both patients and heterozygous carriers of the gene. The gene responsible for the disorder, ATM, has been identified as a member of a family of phosphatidylinositol 3-kinaserelated genes and is one of the master controllers of the networks that are involved in cell cycle control and response to DNA damage. LÄS MER

  4. 8. Aphasia in acute stroke

    Författare :Ann Charlotte Laska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute stroke; aphasia; atrial fibrillation; depression; drug treatment; prognosis; speech and language therapy;

    Sammanfattning : Aphasia is a language impairment due to a brain lesion, usually in the left hemisphere, and is a common symptom in acute stroke. The aims of this thesis were to evaluate aphasia in acute stroke patients, to assess spontaneous language recovery, to evaluate the test instruments, to evaluate the efficacy of drug treatment, and speech and language therapy for recovery of aphasia, and to assess the possibility to reliable identify depression in aphasic patients. LÄS MER

  5. 9. Cellular responses to the DNA damaging cytolethal distending toxin

    Författare :Lina Guerra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytolethal distending toxin (CDT) is a genotoxin, which belongs to a group of bacterial protein toxins called cyclomodulins. These are characterized by their interference with the eukaryotic cell cycle. CDT causes DNA damage, which induces cell cycle arrest and apoptosis. LÄS MER

  7. 10. Role of DNA repair in class switch recombination and somatic hypermutation

    Författare :Likun Du; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Class switch recombination (CSR) and somatic hypermutation (SHM), occurring in the germinal center, are two important processes for B cell development. Both are initiated by activation-induced cytidine deaminase (AID), through deamination of the C residues in the variable and switch regions of the immunoglobulin locus, resulting in either in single stranded or double stranded DNA breaks. LÄS MER