Sökning: "Neurodegenerative disorders"

Visar resultat 1 - 5 av 174 avhandlingar innehållade orden Neurodegenerative disorders.

  1. 1. Objective and subjective aspects related to walking in people with neurodegenerative disorders

    Författare :Magnus Lindh-Rengifo; Aktivt och hälsosamt åldrande; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurodegenerative disorders; parkinson s disease; mild cognitive impairment; gait; walking; perceived walking difficulties; concerns about falling; Neurodegenerative disorders; Parkinson s disease; Mild cognitive impairment; Gait; Walking; Perceived walking difficulties; Concerns about falling;

    Sammanfattning : .... LÄS MER

  3. 2. Development of new affinity proteins for neurodegenerative disorders

    Författare :Linnea C. Hjelm; John Löfblom; Stefan Ståhl; Hanna Lindberg; Ylva Ivarsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein engineering; sequestrins; amyloid beta; alpha-synuclein; phage display; affibodies; blood–brain barrier; Transferrin receptor; receptor-mediated transcytosis; recombinant spider silk; Biotechnology; Bioteknologi;

    Sammanfattning : Neurodegenerative disorders include a full spectrum of diagnoses, including dementias and other neuronal diseases, characterised by degradation of neurons in the brain occurring along with disease progression. Amongst the dementias, the most prevalent are Alzheimer’s (AD) and Parkinson’s disease (PD) that affect millions of people worldwide. LÄS MER

  4. 3. Role of cytokines in experimental neurodegenerative and neuroinflammatory disorders

    Författare :Xing-Mei Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Altered expression of cytokines in response to body injury has diverse actions that can exacerbate, mediate, reduce or inhibit neuronal and myelin damage as well as influence the disease development in a variety of nervous system disorders, such as Alzheimer s disease (AD), multiple sclerosis and Guillain-Barré Syndrome (GBS). In these studies, we attempted to explore the possible roles of tumor necrosis factor (TNF)-α and interleukin (IL)-18 in experimental neurodegenerative and neuroinflammatory disorders. LÄS MER

  5. 4. The role of the ubiquitin-proteasome system in neurodegenerative disorders

    Författare :Lisette Gerridina Gezina Catharina Verhoef; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Degradation; green fluorescent protein GFP ; neurodegeneration; polyglutamine; proteasome; UBB 1; ubiquitin;

    Sammanfattning : Neurodegenerative disorders are a heterogeneous group of clinically and pathologically diverse diseases. The diseases are characterised by selective loss of neurons. in specific regions of the brain. The result is disruption of motor, sensory or cognitive systems, leading to severe disability of the patients. LÄS MER

  7. 5. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders

    Författare :Sara Folkesson Hansson; Göteborgs universitet; []
    Nyckelord :Alzheimer?s disease; frontotemporal dementia; cerebrospinal fluid; neurodegeneration; proteomics; mass spectrometry; prefractionation; protein identification; quantification;

    Sammanfattning : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. LÄS MER