Sökning: "Neural Progenitor Cell"

Visar resultat 41 - 45 av 135 avhandlingar innehållade orden Neural Progenitor Cell.

  1. 41. Use of neural progenitor cell lines and astrocytes for transplantation and gene transfer to the CNS

    Författare :Cecilia Lundberg; CNS Genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fimbria-fornix lesion; NGF; tyrosine hydroxylase; Parkinson s disease; integration; differentiation; temperature-sensitive; grafting; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Intracerebral neuronal transplantation have been shown to ameliorate symptoms of brain dysfunction in both animals models and Parkinson's disease, although problems still remain. The newly introduced technique of ex vivo gene transfer could serve as an alternative approach, possible avoiding some of the draw-backs of the embryonal tissue used in neuronal grafting. LÄS MER

  3. 42. Investigating the role of neural stem/progenitor regulators in the context of brain tumor development

    Författare :Isabelle Leefa Chong San; Stamcellscentrum (SCC); []
    Nyckelord :neural stem progenitor cells; regulators; brain tumor; cell of origin; cancer mechanisms;

    Sammanfattning : Adult neural stem/progenitor cells (NSPs) are multipotent and self-renew over an extensive period of time. Transformation events in such cells, such as genetic or epigenetic alterations can result in brain tumors. LÄS MER

  4. 43. Host responses to human neural cell therapy in spinal cord injury

    Författare :Jia Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Spinal cord injury (SCI) is a devastating condition without a cure. The SCI process comprises an initially mechanical trauma and a secondary cascade of events including a robust inflammatory and immune response. LÄS MER

  5. 44. Neural stem cell therapy and inflammation status of post-traumatic syringomyelia

    Författare :Tingting Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Post-traumatic syringomyelia (PTS) is a severe complication of chronic spinal cord injury (SCI) with intraspinal expanding cysts as the major pathology. PTS occurs in up to 30 % of SCI patients, and time of diagnosis is usually years after the primary injury. LÄS MER

  7. 45. Ionic modulators of stem cell state

    Författare :Anna Omelyanenko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tissue generation during development and maintenance throughout life relies on the proliferation and sequential specification of a group of cells. Stem cells are defined by the properties of self-renewal (division to produce daughter cells equipotent to the mother) and differentiation (division where at least one daughter is of a more restricted potential). LÄS MER