Sökning: "Cysteinyl leukotriene receptors"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Cysteinyl leukotriene receptors.
1. Signalling and trafficking of the cysteinyl leukotriene receptors in intestinal epithelial cells
Sammanfattning : Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. LÄS MER
2. Signaling and regulation of cysteinyl leukotriene receptors in intestinal epithelial cells and colon cancer
Sammanfattning : Colorectal cancer is the third most common type of cancer, and the second leading cause of cancer-related deaths in the Western world. Chronic inflammation, such as inflammatory bowel diseases (IBD), increases the risk of cancer. Cysteinyl leukotrienes are pro-inflammatory mediators that are involved in IBD. LÄS MER
3. Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities
Sammanfattning : .... LÄS MER
4. Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle
Sammanfattning : The cysteinyl leukotrienes (leukotriene C4, D4 and E4) have potent biological actions which significantly contribute to the airway obstruction in asthma. Several of these effects are blocked by drugs known as CysLT1-receptor antagonists, which have been introduced as new treatment for asthma. LÄS MER
5. Leukotrienes and leukotriene receptors : potential roles in cardiovascular diseases
Sammanfattning : Leukotrienes (LTs) are a family of lipid mediators that are involved in host defense and inflammatory responses. They are synthesized from arachidonic acid through the 5-lipoxygenase (5-LO) pathway, and are divided into two classes, the classical chemoattractant leukotriene B4 (LTB4), and spasmogenic cysteinyl leukotrienes (cys-Us) including LTC4, LTD4 and LTE4. LÄS MER