Sökning: "NADH"

Visar resultat 21 - 25 av 98 avhandlingar innehållade ordet NADH.

  1. 21. Bioelectrochemical Applications of Reactions Catalyzed by Immobilized Enzymes

    Författare :Xiao-Jing Tang; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Acetate Kinase.; NAD NADH recycling; Enzyme Electrodes; Enzyme reactors; Enzyme Immobilization; Electrochemical detection; Flow Injection Analysis; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The sensitivity of biosensors can be increased substantially by incorporation in a substrate recycling scheme. Based on the amplification of NAD+/NADH by the recycling reaction catalyzed by glycerol dehydrogenase (GDH) and diaphorase, NAD+/NADH can be determined amperometrically with around 1000 times higher sensitivity than for the substrate sensing mode. LÄS MER

  3. 22. The Membrane-Spanning Domain of Complex I Investigated with Fusion Protein Techniques

    Författare :Maria Trane; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NuoN; NuoM; NuoL; covalent bound heme; Bacillus subtilis; Escherichia coli; membrane protein; His-tag; Cytochrome c; NADH:quinone oxidureductase; fusion protein;

    Sammanfattning : NADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards the quinone binding site(s). LÄS MER

  4. 23. The evolution of respiratory chain complex I from smaller functional modules

    Författare :Vamsi Moparthi; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hyf; Hyc; Membrane bound hydrogenases; NADH:quinone oxidoreductase; Mrp antiporter; 16S rRNA;

    Sammanfattning : NADH:quinone oxidoreductase, or complex I, is a large membrane bound enzyme in the respiratory chain of living organisms, that has evolved from the combination of smaller functional building blocks. The enzyme has a conserved core structure, comprising 14 protein subunits: Seven subunits protrude from the membrane and contain a flavin and eight iron-sulfur clusters. LÄS MER

  5. 24. Labeling, tagging and charging - Long standing issues in bioenergetics addressed with novel techniques

    Författare :Tobias Gustavsson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; WrbA; site specific labeling; fusion proteins; spectro electrochemistry; succinate quinone reductase; NADH quinone oxidoredictase; cytochromes; Respiratory chain;

    Sammanfattning : Understanding the molecular details of bioenergetic processes is fundamentally important. Defects in the mitochondrial energy metabolism can lead to untimely apoptosis and thus cause serious degenerative human diseases. LÄS MER

  7. 25. Palladium(0)-Catalysed Carbonylative Multicomponent Reactions : Synthesis of Heterocycles and the Application of Quinolinyl Pyrimidines as Enzyme Inhibitors

    Författare :Linda Åkerbladh; Mats Larhed; Luke Odell; Anders Karlén; Lise-Lotte Gundersen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium catalysis; Carbonylation; Multicomponent reactions; Domino reactions; Heterocycles; 4-Quinolones; 2-Aminoquinazolinones; Benzoxazinones; N-Acylguanidines; Type II NADH dehydrogenase; NDH-2;

    Sammanfattning : Palladium-catalysed carbonylative multicomponent reactions have proven useful for the synthesis of structurally diverse compounds. Carbon monoxide serves as an atom-efficient, one-carbon building block, which allows for further structural elaboration of the carbonyl compound. LÄS MER