Sökning: "Autoantibodies against GAD65"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Autoantibodies against GAD65.

  1. 1. Organ-specific autoantibodies in Addison's disease and autoimmune polyendocrine syndrome type I

    Författare :Annika Söderbergh; Uppsala universitet; []
    Nyckelord :Medical sciences; Addison s disease; APS I; Down syndrome; AIRE; autoantibodies; autoantigens; autoimmunity; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Assessment of autoantibodies is a valuable tool in the diagnostic procedure of autoimmune diseases. The aim of this study was to investigate the prevalence of different autoantibodies and their associations with disease manifestations in patients with Addison's disease and autoimmune polyendocrine syndrome type I (APS I). LÄS MER

  3. 2. Immunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults (LADA)

    Författare :Magnus Hillman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; diabetology; secreting systems; Isotype class switch; Endocrinology; LADA; Autoantibodies; Autoimmunity; Type 1 diabetes;

    Sammanfattning : Autoimmune diabetes is characterized by cell mediated autoimmunity against insulin producing beta cells in pancreatic islets. Type 1 diabetes is the major cause of diabetes in children and adolescents and is believed to be mediated by a Thl driven destruction of beta cells. LÄS MER

  4. 3. Genetic interaction between Type 1 and Type 2 diabetes

    Författare :Haiyan Li; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; IDDM2.; Insulin gene VNTR; HLA; IDDM1; mixed type 1 2; Mixed type 1 type 2 diabetes families; LADA; GADabs; Autoantibodies against GAD65; Type 1 diabetes; Type 2 diabetes; diabetology; secreting systems; sekretion; diabetologi; Endokrinologi;

    Sammanfattning : There are two major types of diabetes, type 1 and type 2 diabetes. Similarly characterized by hyperglycaemia and long term micro- and macrovascular complications, type 1 and type 2 diabetes have different underlying pathophysiologic processes. In Scandinavia, type 1 diabetes is common; type 2 diabetes accounts for 85% of all cases with diabetes. LÄS MER

  5. 4. Autoantibodies related to type 1 diabetes in children

    Författare :Camilla Skoglund; Johnny Ludvigsson; Rosaura Casas; Outi Vaarala; William Hagopian; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Type 1 diabetes is an autoimmune disease resulting from destruction of the insulin producing beta cells in the pancreas. The patients need life-long heavy treatment and still complications, both acute and later in life, are common. The incidence of type 1 diabetes has increased rapidly during the last decades, especially among young children. LÄS MER

  7. 5. Aspects of autoantibody epitopes in type 1 diabetes

    Författare :Hanna Skärstrand; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Minor autoantigens Neuropeptide Y.; Affinity; ZnT8 autoantibodies; Autoimmune type 1 diabetes;

    Sammanfattning : Type 1 diabetes (T1D) is strongly associated with autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), insulinoma-associated protein 2 (IA-2A) and the most recently identified zinc T8 transporter (ZnT8A). Together or alone, they are important both to predict T1D and to classify diabetes at the time of clinical onset. LÄS MER