Sökning: "N-acylethanolamines"

Hittade 3 avhandlingar innehållade ordet N-acylethanolamines.

  1. 1. Endocannabinoids and N-acylethanolamines in translational pain research : from monoacylglycerol lipase to muscle pain

    Författare :Nazdar Ghafouri; Christopher J Fowler; Andrew SC Rice; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monoacylglycerol lipase; endocannabinoid; palmitoylethanolamide; N-acylethanolamines; microdialysis; chronic widespread pain; muscle pain; trapezius;

    Sammanfattning : In the early nineties cannabinoid receptors, the main target for Δ9-tetrahydrocannabinol (THC), the psychoactive component of marijuana were identified. Shortly after their endogenous ligands, N-arachidonoylethanolamine (anandamide, AEA) and 2-diacylglycerol (2-AG) were characterized. LÄS MER

  2. 2. Endogenous activators of the pain receptor TRPV1 From cell to man

    Författare :Pouya Movahed Rad; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; cannabinoids; capsazepine; N-acylethanolamines; anandamide; blood Circulation; vasodilation; humans; calcitonin Gene-related Peptide; capsaicin; neurogenic inflammation; nociceptors; TRPV1 protein; pain;

    Sammanfattning : N-acylethanolamines (NAEs) belong to a growing family of endogenous signalling molecules acting on a variety of receptors and ion channels. In 1992, it was reported that the N-acylethanolamine anandamide is present in the brain and activates the central cannabinoid (CB) receptor. LÄS MER

  3. 3. Endocannabinoids and Related Lipids in Chronic Pain : Analytical and Clinical Aspects

    Författare :Niclas Stensson; Bijar Ghafouri; Björn Gerdle; Nazdar Ghafouri; Christopher Fowler; Per-Johan Jakobsson; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In Europe, approximately one in five adults experience chronic pain, pain that lasts more than three months. Chronic pain is a significant problem not only for those people suffering from chronic pain but also for society. The prevalence of chronic pain is higher in women and lower socioeconomic groups. LÄS MER