Sökning: "Metalloprotease"

Visar resultat 16 - 20 av 23 avhandlingar innehållade ordet Metalloprotease.

  1. 16. Female stress incontinence and uterovaginal prolapse : collagen turnover and hormone sensitivity in urogenital tissue

    Författare :Lena Edwall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Stress incontinence; urogenital tissue; collagen turnover markers; estradiol- 17beta; estrone; testosterone; uterovaginal prolapse; menopause;

    Sammanfattning : Background: Prevalence of both stress urinary incontinence (SUI) and uterovaginal prolapse (UP) is high and rising with age. Risk factors include multiparity, obesity, chronic obstructive lung disease and previous gynecological surgery. The underlying pathology is still unknown but may include defective connective tissue. LÄS MER

  3. 17. The function of annexin I in human neutrophils. Studies of membrane binding

    Författare :Charlotta Movitz; Göteborgs universitet; []
    Nyckelord :Human neutrophils; secretion; annexin I; grancalcin; subcellular organelles; lipid rafts; DIM;

    Sammanfattning : The neutrophil granulocyte plays an important role in host defense against infections induced by invading microorganisms. The defense mechanism is dependent on the migration of neutrophils from the blood stream to the infected area, where the intruder is phagocytosed and killed. LÄS MER

  4. 18. Human intestinal epithelial cells in innate immunity : interactions with normal microbiota and pathogenic bacteria

    Författare :Gangwei Ou; Sten Hammarström; Marie-Louise Hammarström; Agnes Wold; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immunologi; Immunology;

    Sammanfattning : Rod-shaped bacteria were previously shown to be associated with the small intestinal epithelium of children with celiac disease (CD). Using culture-dependent and independent methods, we characterized the microbiota of small intestine in children with CD and controls. The normal microbiota constitutes an unique organ-specific biofilm. LÄS MER

  5. 19. Outer membrane vesicle-mediated export of virulence factors from Gram-negative bacteria

    Författare :Pramod Kumar Rompikuntal; Sun Nyunt Wai; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Outer membrane vesicles; CDT; PGN; PrtV; Campylobacter jejuni; Vibrio cholerae; Aggregatibacter actinomycetemcomitans; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Gram-negative, motile bacterium Campylobacter jejuni is a causative agent of food-borne gastroenteritis. Cytolethal distending toxin (CDT) is one of the important virulence factors for C. jejuni pathogenesis. It was not previously known how CDT is released from C. LÄS MER

  7. 20. Bacteria-based methods for engineering and characterization of proteases and affinity proteins

    Författare :Lisa Sandersjöö; John Löfblom; Stefan Ståhl; Brent Iverson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioteknologi; Biotechnology;

    Sammanfattning : This thesis is focused on the development of methods for characterization and engineering of both proteases and affinity proteins. In addition, a prodrug concept for small affinity proteins is developed.Two of the developed methods are for engineering and/or characterization of proteases. LÄS MER