Sökning: "Mary jo Wick"

Hittade 2 avhandlingar innehållade orden Mary jo Wick.

  1. 1. Mucosal dendritic cells in inflammatory bowel disease

    Författare :Sa'ad Yislam Salim; Johan D. Söderholm; Mary jo Wick; Linköpings universitet; []
    Nyckelord :Blood; Crohn s disease; dendritic cells; E. coli; FACS; follicle-associated; epithelium; human; ileum; mixed lymphocyte reaction; permeability; Peyer s patches; SAMP1 YitFc; Ussing chambers; villous epithelium; MEDICINE; MEDICIN;

    Sammanfattning : Crohn's disease, a chronic inflammation of the bowel, is a multi-factorial condition where uncontrolled immune responses to luminal bacteria occur in genetically predisposed individuals. The first observable clinical signs are small ulcers that form at a specialised form of epithelium, follicle-associated epithelium (FAB). LÄS MER

  3. 2. Mucosal Vaccination Using Polyacryl Starch Microparticles as Adjuvant with Salmonella enteritidis as a Model Pathogen

    Författare :Lena Strindelius; Ingvar Sjöholm; Mary Jo Wick; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; mucosal vaccination; polyacryl starch microparticles; salmonella enteritidis; flagellin; fimbriae; rCTB; LPS; Ussing chamber; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Polyacryl starch microparticles have been developed as a new mucosal vaccine adjuvant intended for use in oral vaccination. The main objectives of this thesis were to evaluate the efficacy of these polyacryl starch microparticles and to study their uptake through mucosal tissues. LÄS MER