Sökning: "MEDICINE Chemistry"

Visar resultat 31 - 35 av 495 avhandlingar innehållade orden MEDICINE Chemistry.

  1. 31. Crystallization of Parabens : Thermodynamics, Nucleation and Processing

    Författare :Yang Huaiyu; Åke Rasmuson; Joop ter Horst; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nucleation; Induction time; Interfacial energy; Ethyl paraben; Propyl paraben; Butyl paraben; Methanol; Ethanol; Propanol; Acetone; Ethyl acetate; Solubility; Thermodynamics; Activity; Activity coefficient; Liquid-liquid phase separation; Ternary phase diagram; Melting point; Boiling point; Polarity; Cooling crystallization; Sandwich crystal; Porous; Particle Vision and Measurement; Focused Beam Reflectance Method; Infrared Spectroscopy; Confocal Raman Microscopy; X-Ray Diffraction; Differential Scanning Calorimetry; SRA - E-Science SeRC ; SRA - E-vetenskap SeRC ;

    Sammanfattning : In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. LÄS MER

  3. 32. Palladium(0)-Catalysed Carbonylative Multicomponent Reactions : Synthesis of Heterocycles and the Application of Quinolinyl Pyrimidines as Enzyme Inhibitors

    Författare :Linda Åkerbladh; Mats Larhed; Luke Odell; Anders Karlén; Lise-Lotte Gundersen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium catalysis; Carbonylation; Multicomponent reactions; Domino reactions; Heterocycles; 4-Quinolones; 2-Aminoquinazolinones; Benzoxazinones; N-Acylguanidines; Type II NADH dehydrogenase; NDH-2;

    Sammanfattning : Palladium-catalysed carbonylative multicomponent reactions have proven useful for the synthesis of structurally diverse compounds. Carbon monoxide serves as an atom-efficient, one-carbon building block, which allows for further structural elaboration of the carbonyl compound. LÄS MER

  4. 33. Development of low affinity techniques for applications in clinical chemistry

    Författare :Lisa Leickt; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chromatography performance; acute myocardial infarction; antibodies; creatine kinase MB isoforms; lectins; low affinity interactions; weak affinity chromatography; Clinical chemistry; Klinisk kemi;

    Sammanfattning : An increase in the plasma level of creatine kinase MB (CKMB) has long been used to indicate acute myocardial infarction (AMI). For optimal treatment an early diagnosis is important. An increase in the ratio between the two isoforms of CKMB is seen much earlier than an increase in the total level of CKMB. LÄS MER

  5. 34. Theranostic Targeting of GRPR and PSMA in Prostate Cancer

    Författare :Ayman Abouzayed; Anna Orlova; Ulrika Rosenström; Anzhelika Vorobyeva; Bogdan Mitran; Cristina Müller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; gastrin-releasing peptide receptor GRPR ; prostate-specific membrane antigen PSMA ; nuclear medicine; molecular imaging; radiotracers; theranostics; Farmaceutisk vetenskap; Pharmaceutical Science; Oncology; Onkologi;

    Sammanfattning : This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples. LÄS MER

  7. 35. Studies on interfaces between primary and secondary hemostasis

    Författare :Niklas Boknäs; Tomas Lindahl; Lars Faxälv; Jon Gibbins; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Our conceptual understanding of hemostasis is still heavily influenced by outdated experimental models wherein the hemostatic activity of platelets and coagulation factors are understood and studied in isolation. Although perhaps convenient for researchers and clinicians, this reductionist view is negated by an ever increasing body of evidence pointing towards an intimate relationship between the two phases of hemostasis, marked by strong interdependence. LÄS MER