Sökning: "radiotracers"
Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet radiotracers.
1. Diabetes in 3D : β-cell mass assessments in disease models & evaluation of SPECT based imaging
Sammanfattning : Diabetes is a rapidly growing disease with 415 million affected adults worldwide. The pancreatic endocrine cells, most importantly the insulin producing β-cells, play an important role in regulating blood glucose homeostasis. LÄS MER
2. Theranostic Targeting of GRPR and PSMA in Prostate Cancer
Sammanfattning : This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples. LÄS MER
3. Pharmacological properties of radiotracers that measure p-glycoprotein function and density
Sammanfattning : Energy-dependent transporters of the ATP-binding cassette (ABC) family regulate the movement of molecules across cellular membranes. Several of these transporters are expressed in the endothelial cells of brain microvessels (blood-brain barrier) to protect brain tissue from exposure to toxins in the blood. LÄS MER
4. Synthesis of 11C and 18F labelled radiotracers for applications in steroid-related biological systems
Sammanfattning : .... LÄS MER
5. Targeting EGFR and VEGFR2 tyrosine kinases with positron emission tomography : evaluation of two radiotracers
Sammanfattning : Receptor tyrosine kinases (RTKs) are commonly involved in the development, growth and spread of cancer. Targeted therapy with tyrosine kinase inhibitors (TKIs) has proven a successful treatment strategy against cancers in which growth is dependent on the expression of these receptors. LÄS MER