Sökning: "KOLIN"

Hittade 4 avhandlingar innehållade ordet KOLIN.

  1. 1. Epigenetic changes and immunological features of chronic obstructive pulmonary disease

    Författare :Jonas Eriksson Ström; Annelie F. Behndig; Anders Bucht; Anne Lindberg; Erik Melén; Fabbri Leonardo M.; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; immunology; epigenetics; KOLIN; lungmedicin; Lung Medicine; immunologi; Immunology; medicinsk genetik; Medical Genetics;

    Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. LÄS MER

  3. 2. Proteolytic imbalance in COPD : epidemiological and clinical aspects

    Författare :Robert Linder; Anders Blomberg; Anne Lindberg; Annelie F. Behndig; Arne Egesten; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Matrix metalloproteinases; MMP-9; MMP-12; lung function decline; epidemiology; COPD; OLIN; KOLIN; medicin; Medicine;

    Sammanfattning : Background: The complete pathologic mechanism behind the development of chronic obstructive pulmonary disease (COPD) remains unclear, but several risk factors have been identified, of which smoking is the most common. Proteolytic imbalance contributes to lung tissue degradation and is related to both smoking and COPD symptoms. LÄS MER

  4. 3. Detecting prostate cancer metastases - PET/CT and the sentinel node technique

    Författare :Henrik Kjölhede; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Metastases; PET CT; Choline; Fluoride; Sentinel lymph nodes;

    Sammanfattning : Prostate cancer is one of the most common malignancies. Its treatment is highly dependent on the presence or absence of metastases. The available invasive and non-invasive modalities for detecting metastases are imperfect. LÄS MER

  5. 4. Selective protein functionalisation via enzymatic phosphocholination

    Författare :Philipp Ochtrop; Christian Hedberg; Tom Grossmann; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemical biology; organic synthesis; site-selective protein labeling; PTM; phosphocholination; nucleotides; bioorthogonal chemistry; proteomics; IMPDH2;

    Sammanfattning : Proteins are the most abundant biomolecules within a cell and are involved in all biochemical cellular processes ultimately determining cellular function. Therefore, to develop a complete understanding of cellular processes, obtaining knowledge about protein function and interaction at a molecular level is critical. LÄS MER