Sökning: "phosphocholination"

Hittade 2 avhandlingar innehållade ordet phosphocholination.

1. 1. Selective protein functionalisation via enzymatic phosphocholination

   Författare :Philipp Ochtrop; Christian Hedberg; Tom Grossmann; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemical biology; organic synthesis; site-selective protein labeling; PTM; phosphocholination; nucleotides; bioorthogonal chemistry; proteomics; IMPDH2;

   Sammanfattning : Proteins are the most abundant biomolecules within a cell and are involved in all biochemical cellular processes ultimately determining cellular function. Therefore, to develop a complete understanding of cellular processes, obtaining knowledge about protein function and interaction at a molecular level is critical. LÄS MER

3. 2. Synthesis and investigation of bacterial effector molecules

   Författare :Michael Franz Albers; Christian Hedberg; Christian Hackenberger; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial effectors; organic synthesis; Legionella; PTM; peptide synthesis; nucleotide chemistry; Biorganic Chemistry; bioorganisk kemi;

   Sammanfattning : During infections, bacterial microorganisms initiate profound interactions with mammalian host cells. Usually defense mechanisms of the host destroy intruding bacteria in rapid manner. However, many bacterial pathogens have evolved in a way to avoid these mechanisms. LÄS MER