Sökning: "Intestinal health"
Visar resultat 1 - 5 av 468 avhandlingar innehållade orden Intestinal health.
1. Barley malt products for improved intestinal health
Sammanfattning : Barley is a good source of dietary fibre, particularly β-glucan and arabinoxylan, to increase formation of short-chain fatty acids (SCFAs). Butyric and propionic acid are involved in the preservation of colonic barrier function, thus decreasing the risk of inflammation. LÄS MER
2. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers
Sammanfattning : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. LÄS MER
3. Exploring Intestinal Ischemia : An experimental study
Sammanfattning : Background and aims: Unrecognized intestinal mucosal ischemia in severely ill patients may trigger development of multiple organ failure. Such ischemia can be evaluated by intraluminal tonometry reflecting mucosal PCO2 and intramucosal pH (pHi). LÄS MER
4. In vitro-solubility and supersaturation behavior of supersaturating drug delivery systems
Sammanfattning : The development of new pharmaceutical products has been challenged by the growing number of poorly water-soluble drugs, which often lead to suboptimal bioavailability. Various approaches, such as the use of amor-phous solid dispersions and cocrystals, have been used to improve the solu-bility, and subsequent bioavailability, of these drug molecules. LÄS MER
5. Intestinal Mucosa Reconstitution and Protection: Impact of Luminal Factors
Sammanfattning : The gastrointestinal mucosa is one of the most rapidly proliferating tissues in the body, and serves as a barrier to luminal bacteria and toxins. Enteral nutrition, luminal fiber and probiotics are of crucial importance for the integrity of this barrier. LÄS MER