Sökning: "Illumina"
Visar resultat 6 - 10 av 45 avhandlingar innehållade ordet Illumina.
6. DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
Sammanfattning : Type 2 diabetes (T2D) is a common metabolic disease and its prevalence is increasing worldwide. Adipose tissue plays an important role in metabolic processes. Environmental factors may affect metabolic phenotypes and epigenetics may mediate this influence. LÄS MER
7. Microbial DNA Sequencing in Environmental Studies
Sammanfattning : The field of microbial ecology has just entered a new era of rapid technological development and generation of big data. The high-throughput sequencing techniques presently available provide an opportunity to extensively inventorize the blueprints of life. LÄS MER
8. Population level genome-wide association studies in dairy cattle
Sammanfattning : In recent years, genome-wide association studies (GWAS) has become a dominant tool for detecting genetic architectures for complex traits. Thousands of associated genetic variants have been reported. However, the resolution of these studies was limited by the available marker density for the quantitative trait loci (QTL) region. LÄS MER
9. Genome wide methylation analysis and obesity related traits
Sammanfattning : The most studied form of epigenetics is DNA methylation and several studies have investigated the link between the methylome and body weight. In paper I we analyzed the methylation profile of whole blood in 46 subjects measured with Illumina 27K chip. We provide evidence that obesity influences age driven epigenetic changes. LÄS MER
10. Cardiac hypertrophy : transcription patterns, hypertrophic progression and extracellular signalling
Sammanfattning : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. LÄS MER