Sökning: "Glucose Metabolism"

Visar resultat 21 - 25 av 559 avhandlingar innehållade orden Glucose Metabolism.

  1. 21. Towards a comprehensive modeling framework for studying glucose repression in yeast

    Författare :Linnea Österberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; budding yeast; glucose repression; metabolism; mathematical modelling; signaling;

    Sammanfattning : The yeast Saccharomyces cerevisiae is an important model organism for human health and for industry applications as a cell factory. For both purposes, it has been an important organism for studying glucose repression. LÄS MER

  3. 22. Glucose and glycerol transport in adipocytes from a structural perspective

    Författare :Peng Huang; Medicinsk strukturbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; glucose and glycerol metabolism; glucose transporters; aquaglyceroporins; glucose transporter 4; aquaglyceroporin 7; protein and protein interaction; structure; single particle cryo-EM;

    Sammanfattning : Adipocytes are crucial energy reservoirs to maintain metabolic homeostasis of glucose and lipids in the human body.Glucose transporters (GLUTs) and aquaporins (AQPs) play an important role in metabolic regulation of glucose andlipids in human adipocytes. LÄS MER

  4. 23. Systems biology of yeast metabolism - Understanding metabolism through proteomics and constraint-based modeling

    Författare :Carl Malina; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteomics; metabolism; Systems biology; constraint-based modeling; yeast;

    Sammanfattning : Metabolism is the set of all chemical reactions that occur inside of cells. By providing all the building blocks that are required for sustaining a cellular state and cell proliferation, metabolism is at the core of cellular function. Therefore, in order to understand cellular function it is important to understand cellular metabolism. LÄS MER

  5. 24. Links between plasma apoE and glucose metabolism, brain insulin signaling, and synaptic integrity : Relevance to Alzheimer’s disease pathophysiology

    Författare :Anna Edlund; Henrietta Nielsen; William Rebeck; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; apolipoprotein E; insulin; metabolism; Amyloid precursor protein APP ; Fe65; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Human apolipoprotein E (apoE) exists as three main isoforms called apoE2, apoE3, and apoE4, of which the E4 isoform is associated with increased Alzheimer’s disease (AD) risk. Brain glucose hypometabolism, linked to synaptic dysfunction, occurs years before symptom onset in AD, especially in APOEε4-carriers. LÄS MER

  7. 25. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?

    Författare :Assel Sarsenbayeva; Jan Eriksson; Mikael Rydén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; metabolic adverse effects; SGAs; statins; glucocorticoids; glucose uptake; lipolysis; myofibroblasts; fibrosis; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Sammanfattning : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. LÄS MER