Sökning: "SGAs"

Hittade 4 avhandlingar innehållade ordet SGAs.

  1. 1. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?

    Författare :Assel Sarsenbayeva; Jan Eriksson; Mikael Rydén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; metabolic adverse effects; SGAs; statins; glucocorticoids; glucose uptake; lipolysis; myofibroblasts; fibrosis; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Sammanfattning : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. LÄS MER

  3. 2. Capacity allocation mechanisms for grid environments

    Författare :Peter Gardfjäll; Erik Elmroth; Bo Kågström; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Grid computing; capacity allocation; allocation enforcement; accounting; Grid-wide fairshare scheduling; Web services; Computer science; Datavetenskap;

    Sammanfattning : During the past decade, Grid computing has gained popularity as a means to build powerful computing infrastructures by aggregating distributed computing capacity. Grid technology allows computing resources that belong to different organizations to be integrated into a single unified system image – a Grid. LÄS MER

  4. 3. Modulation of the glycoalkaloid biosynthesis pathway in potato (Solanum tuberosum L.) and development of CRISPR/Cas9 methodology for tomato (Solanum lycopersicum L.)

    Författare :Ying Liu; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Steroidal glycoalkaloids (SGAs) are toxic defence substances present in Solanum species, including the tomato and potato. Concerns about SGA toxicity have long been raised regarding table potato cultivars, and more recently regarding starch potato cultivars, where SGAs negatively affect the use of proteins and fibre from starch by-products. LÄS MER

  5. 4. Born too small or too early : effects on blood pressure, renal function and retinal vascularization in adulthood : experimental and clinical studies

    Författare :Anna Kistner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prenatal dexamethasone; SGA; preterm birth; glomerular filtration rate; ambulatory blood pressure; retinal vascularization; IGF-I; IGFBP-1; metabolic serum markers;

    Sammanfattning : Background: Several epidemiological studies the past fifteen years have suggested a connection between fetal growth retardation and later effects on adult health, such as an increased arterial blood pressure and type 2 diabetes mellitus. We studied the effects of fetal growth retardation in an experimental model were pregnant rats where given the synthetic glucocorticoid dexamethasone (DEX). LÄS MER