Sökning: "GAP-43"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet GAP-43.

  1. 1. Regulation of the GAP-43, C-SRC, HASH-1 and ID genes during neuronal differentiation of neuroblastoma cells

    Författare :Eva Örtoft; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Spontaneous correction of fracture deformity : a study in the rat

    Författare :Jian Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Fracture healing; bone modeling; bone turnover; GAP-43; PGP 9.5; CGRP;

    Sammanfattning : The aim of the present study was to elaborate a model in the rat permitting analysis of bone modeling to correct fracture deformity. Among conceivable regulators of this process, the study focused on the peripheral nervous system by analyzing markers of regenerating (GAP-43), mature (PGP 9.5) and sensory (CGRP) nerve fibers at the fracture site. LÄS MER

  4. 3. Alzheimer's disease : towards a multifaceted approach in neuropathological diagnosis

    Författare :Nenad Bogdanovic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alzheimer s disease; CERAD; neurofibrillary tangles. neuritic plaques; apoE. synaptic proteins; rab3a; synaptophysin; synaptotagmin; GAP-43; neurogranin; neuronal degeneration; optical disector 1998;

    Sammanfattning : The main aim of this study has been to investigate potential neuropathological features which may play an important role in understanding the cognitive dysfunction and in making the final diagnosis of Alzheimer's disease (AD). To establish a reliable diagnosis of AD, standardisation and uniformity of the diagnostic protocols must become mandatory. LÄS MER

  5. 4. Regulation of CGRP expression in rat spinal motoneurons

    Författare :Fredrik Piehl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :immunohistochemistry; in situ hybridization; motoneuron; axotomy; peptides; CGRP; trophic factor; FGF; IGF; BDNF; CNTF; GAP-43; cell culture; plasticity; mRNAregulation; regeneration;

    Sammanfattning : The normal distribution and lesion-induced changes in the expression of neuropeptides and growth-related proteins, with special reference to calcitonin gene-related peptide (CGRP),were studied in the motor system of the rat. In addition, factors that influence the expression of CGRP in motoneurons were identified. LÄS MER

  7. 5. Spinal motoneurones and the bulbospinal serotonininergic system in aged rats with behavioral deficits

    Författare :Hans Johnson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :aging; behavior; immunohistochemistry; in situ hybridisation; motoneuron; CGRP; axotorny; GAP-43; neurotrophin receptors; degeneration; axon dystrophy; 5HT TRH; SP; 5HLkA; AADC; serotonintransporter protein; fluoxetine; L-5-HTP;

    Sammanfattning : The expression of neuropeptides, growth-related proteins and neurotrophin receptors were studied in motoneurons of young adult rats and in aged rats with symptoms of neuromuscular incapacities. Also studied were aging-related changes in the descending serotoninergic (5HT) bulbospinal system which constitutes a major afferent pathway to spinal motoneurons. LÄS MER