Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet CNTF.
1. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases
Sammanfattning : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. LÄS MER
2. New neurons and astrocytes in the adult brain. Studies on adult rat neural progenitors in vivo and in vitro with special reference to the effects of IGF-I and CNTF regarding proliferation and lineage determination
Sammanfattning : The hippocampal dentate gyrus in several species, including man, continues to produce new neurons and glial cells in adulthood. The generation of new neurons and glial cells in the adult hippocampus is under strict regulation. Two major events of significance for cell genesis from progenitor cells are proliferation and lineage determination. LÄS MER
Sammanfattning : ÑSpinal cord injury is common in the modern society, often afflictsyoung individuals, and often has devastating consequences. The present workstudies possibilities to obtain better conditions for regeneration of the transectedspinal cord in rats, conditions under which spinal cord grafts are able toestablish structural and functional connections with "natural" targets, andeffects of a series of neurotrophic factors on spinal cord graft survival andgrowth. LÄS MER
Sammanfattning : The normal distribution and lesion-induced changes in the expression of neuropeptidesand growth-related proteins, with special reference to calcitonin gene-related peptide (CGRP),were studied in the motor system of the rat. In addition, factors that influence the expression ofCGRP in motoneurons were identified. LÄS MER
Sammanfattning : Chromaffin cells producing adrenaline or noradrenaline are the predominant celltype in the adrenal medulla, but ganglion cells and Schwann cells are also present. All cells of the adrenal medulla are derived from the neural crest, which is a transient neuroectoderm-derived embryonic structure. LÄS MER