Sökning: "DNA ploidy"

Visar resultat 21 - 25 av 44 avhandlingar innehållade orden DNA ploidy.

  1. 21. Neoadjuvant hormone treatment in localized prostate cancer : a clinical and histopathological study

    Författare :Magnus Hellström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Localized prostate cancer; radical prostatectomy; neo-adjuvant androgen deprivation; GnRH-agonist; histopathology; immunohistochemistry; image analysis; cancer volume; DNA ploidy patterns; PSA in serum; follow-up; prognosisStockholm 1996;

    Sammanfattning : Surgical treatment of localized prostate cancer may be hampered by the spread of cancer through the prostate capsule and in the surgical margins. The prostate is dependent on androgen hormones for its growth and function. LÄS MER

  3. 22. Prediction of prognosis in human breast cancer : a study on clinicopathologic and cytometric prognostic factors

    Författare :Conny Arnerlöv; Stefan O. Emdin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This study was undertaken to evaluate some important prognostic factors in human breast cancer. The prognostic value of accepted clinicopathological factors such as the presence of axillary lymph node métastasés, histologic grade, clinical and pathological stage was confirmed. LÄS MER

  4. 23. Molecular Genetic Alterations In Endometrial And Ovarian Cancers

    Författare :Anjila Koul; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; KRAS; PTEN; TP53; Overexpression; Mutation; Microsatellite instability; Complex atypical hyperplasia; Endometrial cancer; Ovarian cancer; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; CNS metastasis; Cytogenetic analysis; BRCA2; BRCA1; B-catenin; CDKN2A;

    Sammanfattning : Endometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. LÄS MER

  5. 24. Human papillomavirus infection, genetic instability and invasive properties of cervical lesions

    Författare :Barbro Skyldberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical neoplasia; HPV; ISH; PCR; centrosomes; genetic stability; laminin-5;

    Sammanfattning : Cancer of the uterine cervix is one of the most frequent malignancies in women worldwide. Approximately half a million new cases of cervical cancer are diagnosed each year, and about 200 000 women die from the disease. Human papillomavirus (HPV) DNA has been shown to be present in about 90 % of all cervical cancers. LÄS MER

  7. 25. Genome instability, gene expression and prognosis in breast cancer

    Författare :Ulrike Kronenwett; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast adenocarcinoma; genomic instability; SSI; centrosomes;

    Sammanfattning : Aneuploid cancers are regarded as being more malignant than tumors of other ploidy categories, and they are characterized by increased genomic instability. Our investigations resulted in the characterization of an aneuploid subtype of breast carcinoma that proved to be genomically stable. LÄS MER