Sökning: "DNA ploidy patterns"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden DNA ploidy patterns.

  1. 1. Endometrial carcinoma : prognostic factors and protein expression profiling

    Författare :Caroline Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endometrial carcinoma; prognosis; DNA ploidy; MIB-1; p53; laminin-5 72 chain; 2DE;

    Sammanfattning : Endometrial carcinoma is the most common gynaecological cancer in the western world. It is usually diagnosed at an early stage since it presents with irregular vaginal bleeding when the tumour is still limited to the uterus and the prognosis is generally favourable. LÄS MER

  3. 2. Genomic changes defining the progression of human colorectal and cervical tumors

    Författare :Kerstin Heselmeyer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :colorectal; cervical; anal neoplasias proliferation; DNA ploidy; p53 and p21WAF1 expression; HPV; CGH;

    Sammanfattning : Defining changes during the carcinogenesis and progression of tumors is a major way to obtain a better understanding of the mechanisms of cancer development. We therefore investigated the carcinogenesis process in the colon-rectum and in the uterine cervix by different cell chemical, immunohistochemical and cytogenetic methods. LÄS MER

  4. 3. Neoadjuvant hormone treatment in localized prostate cancer : a clinical and histopathological study

    Författare :Magnus Hellström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Localized prostate cancer; radical prostatectomy; neo-adjuvant androgen deprivation; GnRH-agonist; histopathology; immunohistochemistry; image analysis; cancer volume; DNA ploidy patterns; PSA in serum; follow-up; prognosisStockholm 1996;

    Sammanfattning : Surgical treatment of localized prostate cancer may be hampered by the spread of cancer through the prostate capsule and in the surgical margins. The prostate is dependent on androgen hormones for its growth and function. LÄS MER

  5. 4. Primary fallopian tube cancer

    Författare :Ann-Cathrin Hellström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :primary fallopian tube cancer; prognosis; symtoms; treatment; staging; DNA ploidy; cell proliferation; tumor angiogenesis; p53; p21WAF I expression; HPV; CGH; PCRSSCP; CDGE;

    Sammanfattning : Primary fallopian tube cancer (PFTC) is a rare and aggressive gynecologic malignancy and it accounts for less than 5% of all genital female cancers according to the Swedish Cancer Registry. In a retrospective study we have analysed histopathological, clinical, biological and prognostic factors among patients with PFTC. LÄS MER

  7. 5. Biopsies, diagnosis and prognosis in prostate cancer

    Författare :Lars Häggarth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer is the third most common cancer in men worldwide, and poses a challenge both for patients and health care systems. Many aspects of prostate cancer are controversial, from screening for early detection to the concept of insignificant cancer that does not need curative treatment. LÄS MER