Sökning: "Contributing factors"

Visar resultat 21 - 25 av 582 avhandlingar innehållade orden Contributing factors.

  1. 21. Aspects of T cell development contributing to autoimmunity

    Författare :Maria Carlsén; Diabetes - immunovirologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FTOC; T cell development; Type 1 diabetes; p53; Insulin; NOD; Negative selection; TGF-β; Tolerance; Thymus; Conditional cre lox knock out; Autoimmunity;

    Sammanfattning : Autoimmunity, such as type 1 diabetes (T1D), arises as a result of tolerance breakdown against host tissues, i.e. the β-cells. Central tolerance is established during thymic T cell development and defects in key events during this process could contribute to the pathogenesis of autoimmune diseases. LÄS MER

  2. 22. Opening the Black Box of Community-Based Injury Prevention Programmes : Towards Improved Understanding of Factors that Influence Programme Effectiveness

    Författare :Per Nilsen; Kent Lindqvist; Lennart Nordenfelt; Toomas Timpka; Gunnar Tellnes; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Community-based; injury prevention; programmes; evaluation; effectiveness; Samhällsbaserad; skadeprevention; program; utvärdering; effektivitet; Public health science; Folkhälsovetenskap;

    Sammanfattning : Despite wide application of community-based programmes to prevent injuries and promote health over the last 25 years, there is a paucity of evaluations from which to obtain evidence regarding the effectiveness and critical factors contributing to achieving effectiveness of these programmes. Research on community-based injury prevention programmes thus far has been driven by the question “does it work?” However, merely establishing whether a programme works or not provides insufficient information to generate new knowledge about these programmes. LÄS MER

  3. 23. Impact of genetic and environmental factors in intestinal inflammation

    Författare :Oscar Eduardo Diaz Perez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The gastrointestinal tract, is continuously exposed to a wide variety of stimuli, including dietary-derived metabolites, environmental compounds and the microbiota. Since these antigens can be beneficial or detrimental for the organism, proper sensing of the luminal content is essential for orchestrating both pro-inflammatory and tolerogenic immune responses on demand and therefore, ensure the establishment of intestinal homeostasis. LÄS MER

  4. 24. Inequalities in Health : the Importance of Material/Structural Factors and Psychosocial Resources

    Författare :Fredrik Granström; Margareta Kristenson; Anu Molarius; Peter Garvin; Urban Janlert; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Socioeconomic inequalities in health are well-documented in most countries. Health differences have been shown to follow a gradient, where health status in average is somewhat poorer for every lower level in the social hierarchy. Notably, the welfare state Sweden is no exception. LÄS MER

  5. 25. On the identification and prevention of ergonomic risk factors : with special regard to reported occupational injuries of the musculo-skeletal system

    Författare :Kristina Kemmlert; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Industrial Work Environment; Industriell produktionsmiljö;

    Sammanfattning : A checklist for the screening of ergonomic risks was designed, evaluated and applied at work place assessments. Training for measurements for the revised NIOSH lifting equation was described and the inter-observer reliability discussed. LÄS MER