Sökning: "Cohort analysis"

Visar resultat 16 - 20 av 1043 avhandlingar innehållade orden Cohort analysis.

  1. 16. Metabolic factors and bladder cancer risk and mortality. Studies to approach causal associations and interactions with smoking and genetic variants

    Författare :Stanley Teleka; Registerbaserad epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder cancer; metabolic factors; Association; Interaction; Blood pressure; BMI; statistical analysis; Mendelian Randomization Analysis;

    Sammanfattning : Urothelial bladder cancer (BC) is one of the most common cancers in developed countries. It has one of the highest recurrence rates among solid tumors, resulting in regular treatment and follow-up, making it one of the most expensive cancers to treat, and a significant public health burden. LÄS MER

  3. 17. On the analysis of antibody repertoires

    Författare :August Jernbom Falk; Peter Nilsson; Anna Månberg; Albert J.R. Heck; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody repertoire; autoantibodies; serology; microarray; bead array; affinity proteomics; psychosis; SARS-CoV-2; COVID-19; post-COVID-19 condition; immunoglobulin; IgG; Biotechnology; Bioteknologi;

    Sammanfattning : The antibody repertoire is the ensemble of antibodies found in an individual at a given time. It displays high heterogeneity between individuals while being both largely temporally stable within an individual and rapidly responsive to immunological challenge. LÄS MER

  4. 18. Stage T1 Urinary Bladder Carcinoma : Investigation of A Population-Based Cohort

    Författare :Hans Olsson; Staffan Jahnson; Per Hultman; Peter Söderkvist; Sten Nilsson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Approximately 2 300 new cases of urinary bladder carcinoma (UBC) are diagnosed every year in Sweden. This type of cancer is characterized as a long-standing disease with a high risk of recurrence and progression from an indolent to a more aggressive course. LÄS MER

  5. 19. Functional analysis of genetic risk markers

    Författare :Jesper Robert Gådin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regulatory variants are the main factors responsible for genetic predisposition to how e.g. humans react differently to the environment. LÄS MER

  7. 20. Sequence based analysis of neurodevelopmental disorders

    Författare :Jonatan Halvardson; Lars Feuk; Alexandre Reymond; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Genetics; Medicinsk genetik;

    Sammanfattning : In this thesis the main focus is the use of methods and applications of next generation sequencing in order to study three of the most common neurodevelopmental disorders: intellectual disability, epilepsy and schizophrenia. A large fraction of the genes in our genome produce several distinct transcript isoforms through the process of splicing and there is an increasing amount of evidence pinpointing mutations affecting splicing as a mechanism of disease. LÄS MER