Sökning: "Mendelian Randomization Analysis"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Mendelian Randomization Analysis.
1. Optimizing Exposome-wide Assessments in Cardiometabolic Risk
Sammanfattning : This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. In our work, we aim to improve the identification of individuals at-risk of cardiometabolic disease through the characterization of complex environmental exposures (i.e. LÄS MER
2. Metabolic factors and bladder cancer risk and mortality. Studies to approach causal associations and interactions with smoking and genetic variants
Sammanfattning : Urothelial bladder cancer (BC) is one of the most common cancers in developed countries. It has one of the highest recurrence rates among solid tumors, resulting in regular treatment and follow-up, making it one of the most expensive cancers to treat, and a significant public health burden. LÄS MER
3. Interplay between genetics and environment in obesity
Sammanfattning : Background. Being one of the largest current global health problems, obesity is a result of interplay between genetic and environmental factors. LÄS MER
4. Insulin Resistance : Causes, biomarkers and consequences
Sammanfattning : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. LÄS MER
5. Modifiable risk factors, blood proteins, and venous thromboembolism
Sammanfattning : Venous thromboembolism (VTE) refers to blood clots in the veins, which is an underappreciated vascular disease that can cause disability and mortality. Although some triggers for VTE (e.g. LÄS MER