Sökning: "Cellbiology"

Visar resultat 6 - 10 av 51 avhandlingar innehållade ordet Cellbiology.

  1. 6. Regulation of a Transcription Factor Activating Protease

    Författare :Deike J. Omnus; Per O. Ljungdahl; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Latent Transcription Factors; Protease; Phosphorylation; Proteasome; Signal Transduction; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : .... LÄS MER

  3. 7. Ribosomal proteins L5 and L15 : Functional characterisation of important features, in vivo

    Författare :Ivailo Simoff; Odd Nygård; Gustavo Nader; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; cellbiologi; Cellbiology;

    Sammanfattning : Protein synthesis is a highly regulated and energy consuming process, during which a large ribonucleoprotein particle called the ribosome, synthesizes new proteins. The eukaryotic ribosome consists of two unequal subunits called: small and large subunits. Both subunits are composed of ribosomal RNA (rRNA) and ribosomal proteins (r-proteins). LÄS MER

  4. 8. Tropomyosin in Normal and Malignant Cells and the Action of Picropodophyllin on the Microfilament and Microtubule Systems

    Författare :Li-Sophie Zhao Rathje; Uno Lindberg; Roger Karlsson; J. Victor Small; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tropomyosin; Actin; Picropodophyllin; Tubulin; Cell motility; Cancer; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : Cell motility is a fundamental process, enabling cells to migrate, for instance during embryogenesis, tissue repair and defense. Force is generated by two protein systems, which also participate in cell proliferation, control macromolecular and organelle distribution and determine the fine structure of the cell interior. LÄS MER

  5. 9. Molecular And Cellular Networks in Critical Illness Associated Muscle Weakness : Skeletal Muscle Proteostasis in the Intensive Care Unit

    Författare :Varuna Chaminda Banduseela; Lars Larsson; Gustavo Nader; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperones; autophagy; intensive care unit; heat shock proteins; protein synthesis; proteostasis; ER stress; gene expression; sepsis; neuromuscular blockers; corticosteroids; immobilisation; mechanical ventilation; Molekylär cellbiologi; Molecular Cellbiology; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Critical illness associated muscle weakness and muscle dysfunction in intensive care unit (ICU) patients lead to severe morbidity and mortality as well as significant adverse effect on quality of life. Immobilization, mechanical ventilation, neuromuscular blocking agents, corticosteroids, and sepsis have been implicated as important risk factors, but the underlying molecular and cellular mechanisms remain unclear. LÄS MER

  7. 10. Modeling Neural Stem Cell and Glioma Biology

    Författare :Tobias Bergström; Karin Forsberg-Nilsson; Staffan Johansson; Sven Påhlman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; integrins; glioma; PDGF; mast cell; Molekylär cellbiologi; Molecular Cellbiology; Oncology; Onkologi;

    Sammanfattning : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. LÄS MER