Sökning: "CRD"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet CRD.

  1. 1. Use of Recombinant Allergens for Component-Resolved Diagnostics (CRD) in IgE-Mediated Allergy

    Författare :Åsa Marknell DeWitt; Pia Ek; Jonas Lidholm; Ronald van Ree; Uppsala universitet; []
    Nyckelord :Biomedical laboratory science; recombinant allergen; IgE; component-resolved diagnostics; CRD; tropomyosin; Phl p 11; Phl p 4; Pen a 1; Hev b 5; Biomedicinsk laboratorievetenskap;

    Sammanfattning : Immunoglobulin E (IgE)-mediated allergy occurs when our immune system causes a reaction to otherwise harmless substances (allergens). Allergens are predominantly proteins present in biological materials such as pollens, mites, animal epithelia, moulds and foods. LÄS MER

  3. 2. Functional properties of galectin-3. Beyond the sugar binding

    Författare :Adriana Lepur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-3; galectin-1; M1 macrophage; M2 macrophage; self-association; fluorescence anisotropy; citrus pectin; galactomannane;

    Sammanfattning : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. LÄS MER

  4. 3. Structural insights into glycoprotein transport and viral escape

    Författare :Lucas Malard Velloso; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :X-ray crystallography; glycoprotein transport; endoplasmic reticulum; p58 ERGIC-53; MHC class I molecules; viral escape;

    Sammanfattning : The correct trafficking of proteins through the secretory pathway is essential for the maintenance of cellular functions. Increasing evidence suggests that at least for some glycoproteins, export from the endoplasmic reticulum (ER) is mediated by interaction with cargo receptors. LÄS MER

  5. 4. Get in tune : chloroplast and nucleus harmony

    Författare :Dmitry Kremnev; Åsa Strand; Francis-Andre Wollman; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; chloroplast; development; gene expression;

    Sammanfattning : Photosynthetic eukaryots emerged as a result of several billion years of evolution between proeukaryotic cell and ancestral cyanobacteria that formed modern chloroplasts. The symbiotic relationship led to significant rearrangements in the genomes of the plastid and the nucleus: as many as 90 % of all the plastid genes were transferred to the nucleus. LÄS MER

  7. 5. Sensory and secretory responses to intestinal distension; implications for the pathophysiology of the irritable bowel syndrome

    Författare :Marie Larsson; Göteborgs universitet; []
    Nyckelord :irritable bowel syndrome; secretion; transmucosal potential difference; migrating motor complex; colorectal distension; visceral sensitivity; colitis; enteric nervous system; rat; mouse;

    Sammanfattning : Irritable bowel syndrome (IBS) is a common gut disorder, characterized by abdominal pain and/or discomfort associated with disturbed bowel habits. The pathophysiology of IBS is complex and still largely unknown, although visceral hypersensitivity is frequently associated with the disease. LÄS MER