Sökning: "recombinant allergen"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden recombinant allergen.

  1. 1. Use of Recombinant Allergens for Component-Resolved Diagnostics (CRD) in IgE-Mediated Allergy

    Författare :Åsa Marknell DeWitt; Pia Ek; Jonas Lidholm; Ronald van Ree; Uppsala universitet; []
    Nyckelord :Biomedical laboratory science; recombinant allergen; IgE; component-resolved diagnostics; CRD; tropomyosin; Phl p 11; Phl p 4; Pen a 1; Hev b 5; Biomedicinsk laboratorievetenskap;

    Sammanfattning : Immunoglobulin E (IgE)-mediated allergy occurs when our immune system causes a reaction to otherwise harmless substances (allergens). Allergens are predominantly proteins present in biological materials such as pollens, mites, animal epithelia, moulds and foods. LÄS MER

  2. 2. Novel allergen preparations for use in allergen-specific immunotherapy

    Författare :Theresa Neimert Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Allergy; allergen-specific immunotherapy; adjuvants; carbohydrate-based particles; allergic asthma; mouse models; hypoallergens;

    Sammanfattning : Allergy is a common disease in the industrialized countries, affecting approximately 25% of the population. Therefore, there is a need to find new treatment strategies to improve the quality of life for allergic individuals. Today the only treatment that gives long-lasting reduction of allergic symptoms is allergen-specific immunotherapy (SIT). LÄS MER

  3. 3. A study of allergens in the mite Lepidoglyphus destructor, using monoclonal antibodies and recombinant techniques

    Författare :Susanna Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; allergen; characterization; dust mite; IgE-reactivity; monoclonal antibody; recombinant allergen; site-directed mutagenesis;

    Sammanfattning : Mites are one of the most common causes of allergic reactions in many parts of the world. They can broadly be divided into two categories: house dust mites, primarily found in dwellings, and storage mites, primarily found in farming environments and grain storage facilities. Storage mites have now also been shown to exist in house dust. LÄS MER

  4. 4. Identification and characterization of allergen components of the opportunistic yeast Malassezia furfur

    Författare :Arezou Zargari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; allergen; atopic dermatitis; baculovirus; Candida albicans; CAP RAST; cDNA; confocal laser scanning microscopy; Escherichia coli; IgE; Malassezia furfur; monoclonal antibody; Pityrosporum orbiculare; recombinant allergen; yeast.;

    Sammanfattning : The yeast Malassezia furfur (Pityrosporum orbiculare) is a member of the human norrnal skin microflora. It has been suggested that this yeast plays an important role in the pathogenesis of atopic dermatitis (AD). In 40-65% of patients with AD anti-M. furfur activity has been shown with skin tests and/or specific IgE serology. LÄS MER

  5. 5. Recombinant cat and mite allergens as tools in the study of diagnosis and treatment of allergy

    Författare :Tiiu Saarne; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Allergic diseases, such as allergic asthma, allergic rhinitis and atopic eczema, are a major health problem world-wide, affecting up to 30% of the population. A large proportion of the patients are allergic to indoor allergens, such as mite and cat allergens, which are airborne and thus cause symptoms in the airways upon inhalation. LÄS MER