Sökning: "Biomedicinsk strålningsvetenskap"

Visar resultat 21 - 25 av 34 avhandlingar innehållade orden Biomedicinsk strålningsvetenskap.

  1. 21. Harnessing the molecular Trojan horse : Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor

    Författare :Gillian Bonvicini; Stina Syvänen; Johanna Fälting; Dag Sehlin; Ken Honek; Sahar Roshanbin; Joy Zuchero; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transferrin receptor TfR ; bispecific antibody; brain delivery; positron emission tomography PET ; Alzheimer’s disease; pharmacokinetics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Sammanfattning : With high specificity and selectivity to targets, antibodies are prime candidates for positron emission tomography (PET) radioligands. They do not passively cross the blood-brain barrier which has hindered their development for imaging intrabrain targets, like amyloid-β (Aβ) in Alzheimer’s disease. LÄS MER

  3. 22. Expressions of mercury-selenium interaction in vitro

    Författare :Peter Frisk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; growth inhibition; inorganic mercury; interaction; organic mercury; selenite; selenomethionine; toxicity; uptake; Onkologi; Oncology; Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Interaction between mercury and selenium has previously been observed both in man and in animals. The aim of this work was to study expressions of interaction between mercury and selenium in human K-562 cells. LÄS MER

  4. 23. Biomechanical assessment of head and neck movements in neck pain using 3D movement analysis

    Författare :Helena Grip; Gertjan Ettema; Umeå universitet; []
    Nyckelord :movement analysis; kinematics; helical axis; neck pain; whiplash; cervical spine; pattern classification; motor control; head-eye co-ordination; head movement; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : Three-dimensional movement analysis was used to evaluate head and neck movement in patients with neck pain and matched controls. The aims were to further develop biomechanical models of head and neck kinematics, to investigate differences between subjects with non-specific neck pain and whiplash associated disorders (WAD), and to evaluate the potential of objective movement analysis as a decision support during diagnosis and follow-up of patients with neck pain. LÄS MER

  5. 24. Spatio-temporal processing of surface electromyographic signals : information on neuromuscular function and control

    Författare :Christer Grönlund; Leif Sörnmo; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; EMG; multichannel surface electromyography; motor unit action potentials; conduction velocity; muscle architecture; signal quality; spatial distributions; synchronization; muscle function; motor control; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : During muscle contraction, electrical signals are generated by the muscle cells. The analysis of those signals is called electromyography (EMG). The EMG signal is mainly determined by physiological factors including so called central factors (central nervous system origin) and peripheral factors (muscle tissue origin). LÄS MER

  7. 25. Tumour targeting with stable and radioactive nuclides : Dosimetric aspects at the cellular level

    Författare :Torbjörn Hartman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; Oncology; Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Targeting with radioactive nuclides or nuclides that can be activated by neutrons may be a powerful tool for treatment of invasive tumours and disseminated tumour cells. The targeting agents are designed to find tumour cells and deliver the nuclides. LÄS MER