Sökning: "BMP signaling"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden BMP signaling.

  1. 11. Control of early development of the lens and the retina

    Författare :Tanushree Pandit; Lena Gunhaga; Paola Bovolenta; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lens; retina; BMP; FGF; chick; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The nervous system is composed of two separate compartments, the central and the peripheral nervous system. The peripheral nervous system (PNS) composed mainly of sensory organs transmits sensory information to the central nervous system (CNS) comprising the brain and the spinal cord. LÄS MER

  3. 12. Pharmacological manipulation of fracture healing and bone remodeling

    Författare :Anna Kajsa Harding; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pin-fixation; fracture healing; bone remodeling; bone graft; Bisphosphonate; BMP;

    Sammanfattning : Drug treatment has been and will continue to be a successful method in modern medicine that can change the course of a disease. However, it is surprisingly seldom used in the more technically oriented orthopedic surgery. LÄS MER

  4. 13. Directing stem cells and progenitors towards neuronal differentiation - implications for experimental therapies for Parkinson's disease

    Författare :Anke Brederlau; Göteborgs universitet; []
    Nyckelord :stem cells; Parkinson s disease; progenitors; BMP; ASK1; dopamine;

    Sammanfattning : The insight that stem- and progenitor-cells contribute to replacement of nerve cells in the adult central nervous system is the basis of modern therapies for structural brain repair. Their goal is to protect, support and stimulate endogenous stem cells in areas affected by disease and to replace lost cells by transplanting in vitro generated, tailored nerve cells. LÄS MER

  5. 14. TGF-β Family Signaling in Tumor Angiogenesis

    Författare :Nikolas Eleftheriou; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Angiogenesis provides growing tumors a source of nutrients and oxygen, and a route for metastatic dissemination. In recent years anti-angiogenic therapies that primarily target the vascular endothelial growth factor (VEGF) signaling cascade have entered the clinic. LÄS MER

  7. 15. Novel Regulators of the TGF-β Signaling Pathway

    Författare :Marcin Kowanetz; Aristidis Moustakas; Carl-Henrik Heldin; Caroline Hill; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-β; Smad; Id; EMT; cell cycle; SNF1LK; ubiquitin; degradation; signal transduction; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The transforming growth factor-β (TGF-β) superfamily consists of related multifunctional cytokines, which include TGF-βs, activins, and bone morphogenetic proteins (BMPs) and coordinate several biological responses in diverse cell types. The biological activity of TGF-β members is executed by transmembrane serine/threonine kinase receptors and intracellular Smad proteins. LÄS MER